Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation

JAHR Claassen, DHJ Thijssen… - Physiological …, 2021 - journals.physiology.org
Brain function critically depends on a close matching between metabolic demands,
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …

Functional near-infrared spectroscopy and its clinical application in the field of neuroscience: advances and future directions

WL Chen, J Wagner, N Heugel, J Sugar… - Frontiers in …, 2020 - frontiersin.org
Similar to functional magnetic resonance imaging (fMRI), functional near-infrared
spectroscopy (fNIRS) detects the changes of hemoglobin species inside the brain, but via …

Pathophysiology of delayed cerebral ischemia after subarachnoid hemorrhage: a review

WS Dodd, D Laurent, AS Dumont… - Journal of the …, 2021 - Am Heart Assoc
Delayed cerebral ischemia is a major predictor of poor outcomes in patients who suffer
subarachnoid hemorrhage. Treatment options are limited and often ineffective despite many …

Delayed neurological deterioration after subarachnoid haemorrhage

RL Macdonald - Nature Reviews Neurology, 2014 - nature.com
Subarachnoid haemorrhage (SAH) causes early brain injury (EBI) that is mediated by effects
of transient cerebral ischaemia during bleeding plus effects of the subarachnoid blood …

Transfer function analysis of dynamic cerebral autoregulation: a white paper from the International Cerebral Autoregulation Research Network

JAHR Claassen… - Journal of Cerebral …, 2016 - journals.sagepub.com
Cerebral autoregulation is the intrinsic ability of the brain to maintain adequate cerebral
perfusion in the presence of blood pressure changes. A large number of methods to assess …

Aneurysmal subarachnoid hemorrhage

S D'Souza - Journal of neurosurgical anesthesiology, 2015 - journals.lww.com
Aneurysmal subarachnoid hemorrhage (SAH) is a worldwide health burden with high fatality
and permanent disability rates. The overall prognosis depends on the volume of the initial …

Brain ultrasonography: methodology, basic and advanced principles and clinical applications. A narrative review

C Robba, A Goffi, T Geeraerts, D Cardim, G Via… - Intensive care …, 2019 - Springer
Brain ultrasonography can be used to evaluate cerebral anatomy and pathology, as well as
cerebral circulation through analysis of blood flow velocities. Transcranial colour-coded …

Controversies and evolving new mechanisms in subarachnoid hemorrhage

S Chen, H Feng, P Sherchan, D Klebe, G Zhao… - Progress in …, 2014 - Elsevier
Despite decades of study, subarachnoid hemorrhage (SAH) continues to be a serious and
significant health problem in the United States and worldwide. The mechanisms contributing …

The pathophysiology and treatment of delayed cerebral ischaemia following subarachnoid haemorrhage

KP Budohoski, M Guilfoyle, A Helmy… - Journal of Neurology …, 2014 - jnnp.bmj.com
Cerebral vasospasm has traditionally been regarded as an important cause of delayed
cerebral ischaemia (DCI) which occurs after aneurysmal subarachnoid haemorrhage, and …

Regulation of the cerebral circulation: bedside assessment and clinical implications

J Donnelly, KP Budohoski, P Smielewski, M Czosnyka - Critical care, 2016 - Springer
Regulation of the cerebral circulation relies on the complex interplay between
cardiovascular, respiratory, and neural physiology. In health, these physiologic systems act …