A transdiagnostic systematic review and meta-analysis of ketamine's anxiolytic effects

H Hartland, K Mahdavi, LA Jelen… - Journal of …, 2023 - journals.sagepub.com
Background: Ketamine may be effective in treating symptoms of anxiety, but the time profile
of ketamine's anxiolytic effect is ill-defined. This systematic review and meta-analysis …

Pharmacometabolomics in drug disposition, toxicity and precision medicine

GR Trevor, YJ Lim, BL Urquhart - Drug Metabolism and Disposition, 2024 - ASPET
The precision medicine initiative has driven a substantial change in the way scientists and
health care practitioners think about diagnosing and treating disease. While it has long been …

Perspectives on the impact of vortioxetine on the treatment armamentarium of major depressive disorder

A Cuomo, G Barillà, M Cattolico… - Expert Review of …, 2024 - Taylor & Francis
ABSTRACT Introduction Major Depressive Disorder (MDD) is a mental health issue that
significantly affects patients' quality of life and functioning. Despite available treatments …

Rhyme or reason in therapeutics

J Cookson, J Pimm - BJPsych Advances, 2023 - cambridge.org
As the bewildered slave Dromio complains in one of Shakespeare's earliest plays, our
actions need 'rhyme or reason'or we are lost in a 'comedy of errors'. In his case the error …

[HTML][HTML] Fostering visual plasticity: the crucial role of neurotrophin receptor TRKB

C Cannarozzo - 2024 - helda.helsinki.fi
The brain demonstrates remarkable adaptability during early development, responding to
internal and external stimuli through plasticity. Different sensory systems undergo critical …

O modelo de depressão da Bulbectomia Olfatória Bilateral em Ratos Wistar induz o aumento da expressão gênica de receptores A1 de Adenosina em hipocampo.

SAA Santos - 2022 - repositorio.ufop.br
O transtorno depressivo maior (TDM) é um transtorno psiquiátrico altamente prevalente que
afeta milhões de pessoas em todo o mundo. Acredita-se que o TDM não possui uma única …