[HTML][HTML] SARS-CoV-2 vaccines in advanced clinical trials: Where do we stand?
The ongoing SARS-CoV-2 pandemic has led to the focused application of resources and
scientific expertise toward the goal of developing investigational vaccines to prevent COVID …
scientific expertise toward the goal of developing investigational vaccines to prevent COVID …
[HTML][HTML] Current status of Zika virus vaccines: successes and challenges
The recently emerged Zika virus (ZIKV) spread to the Americas, causing a spectrum of
congenital diseases including microcephaly in newborn and Guillain-Barré syndrome (GBS) …
congenital diseases including microcephaly in newborn and Guillain-Barré syndrome (GBS) …
The Impact of IgG transplacental transfer on early life immunity
Pediatric vaccines have significantly reduced infectious disease–related infant mortality, but
as protective immunity often requires several infant vaccine doses, maternally acquired Abs …
as protective immunity often requires several infant vaccine doses, maternally acquired Abs …
Zika vaccine development: current status
GA Poland, IG Ovsyannikova, RB Kennedy - Mayo Clinic Proceedings, 2019 - Elsevier
Zika virus outbreaks have been explosive and unpredictable and have led to significant
adverse health effects—as well as considerable public anxiety. Significant scientific work …
adverse health effects—as well as considerable public anxiety. Significant scientific work …
[HTML][HTML] A nanostructured lipid carrier for delivery of a replicating viral RNA provides single, low-dose protection against Zika
JH Erasmus, AP Khandhar, J Guderian, B Granger… - Molecular Therapy, 2018 - cell.com
Since the first demonstration of in vivo gene expression from an injected RNA molecule
almost two decades ago, 1 the field of RNA-based therapeutics is now taking significant …
almost two decades ago, 1 the field of RNA-based therapeutics is now taking significant …
A double-blind, randomized, placebo-controlled phase 1 study of Ad26. ZIKV. 001, an Ad26-vectored anti–Zika virus vaccine
NC Salisch, KE Stephenson, K Williams… - Annals of internal …, 2021 - acpjournals.org
Background: Zika virus (ZIKV) may cause severe congenital disease after maternal–fetal
transmission. No vaccine is currently available. Objective: To assess the safety and …
transmission. No vaccine is currently available. Objective: To assess the safety and …
Flavivirus infection—A review of immunopathogenesis, immunological response, and immunodiagnosis
Flaviviruses are group of single stranded RNA viruses that cause severe endemic infection
and epidemics on a global scale. It presents a significant health impact worldwide and the …
and epidemics on a global scale. It presents a significant health impact worldwide and the …
[HTML][HTML] Zika virus vaccines
P Abbink, KE Stephenson, DH Barouch - Nature Reviews Microbiology, 2018 - nature.com
The recent epidemic of Zika virus (ZIKV) in the Americas has revealed the devastating
consequences of ZIKV infection, particularly in pregnant women. Congenital Zika syndrome …
consequences of ZIKV infection, particularly in pregnant women. Congenital Zika syndrome …
A recombinant platform for flavivirus vaccines and diagnostics using chimeras of a new insect-specific virus
J Hobson-Peters, JJ Harrison, D Watterson… - Science translational …, 2019 - science.org
Flaviviruses such as dengue, yellow fever, Zika, West Nile, and Japanese encephalitis virus
present substantial global health burdens. New vaccines are being sought to address safety …
present substantial global health burdens. New vaccines are being sought to address safety …
Drugs for the treatment of Zika virus infection
JA Bernatchez, LT Tran, J Li, Y Luan… - Journal of medicinal …, 2019 - ACS Publications
Zika virus is an emerging flavivirus that causes the neurodevelopmental congenital Zika
syndrome and that has been linked to the neuroinflammatory Guillain–Barré syndrome. The …
syndrome and that has been linked to the neuroinflammatory Guillain–Barré syndrome. The …