[HTML][HTML] SARS-CoV-2 vaccines in advanced clinical trials: Where do we stand?

S Chakraborty, V Mallajosyula, CM Tato, GS Tan… - Advanced drug delivery …, 2021 - Elsevier
The ongoing SARS-CoV-2 pandemic has led to the focused application of resources and
scientific expertise toward the goal of developing investigational vaccines to prevent COVID …

[HTML][HTML] Current status of Zika virus vaccines: successes and challenges

A Pattnaik, BR Sahoo, AK Pattnaik - Vaccines, 2020 - mdpi.com
The recently emerged Zika virus (ZIKV) spread to the Americas, causing a spectrum of
congenital diseases including microcephaly in newborn and Guillain-Barré syndrome (GBS) …

The Impact of IgG transplacental transfer on early life immunity

GG Fouda, DR Martinez, GK Swamy, SR Permar - Immunohorizons, 2018 - journals.aai.org
Pediatric vaccines have significantly reduced infectious disease–related infant mortality, but
as protective immunity often requires several infant vaccine doses, maternally acquired Abs …

Zika vaccine development: current status

GA Poland, IG Ovsyannikova, RB Kennedy - Mayo Clinic Proceedings, 2019 - Elsevier
Zika virus outbreaks have been explosive and unpredictable and have led to significant
adverse health effects—as well as considerable public anxiety. Significant scientific work …

[HTML][HTML] A nanostructured lipid carrier for delivery of a replicating viral RNA provides single, low-dose protection against Zika

JH Erasmus, AP Khandhar, J Guderian, B Granger… - Molecular Therapy, 2018 - cell.com
Since the first demonstration of in vivo gene expression from an injected RNA molecule
almost two decades ago, 1 the field of RNA-based therapeutics is now taking significant …

A double-blind, randomized, placebo-controlled phase 1 study of Ad26. ZIKV. 001, an Ad26-vectored anti–Zika virus vaccine

NC Salisch, KE Stephenson, K Williams… - Annals of internal …, 2021 - acpjournals.org
Background: Zika virus (ZIKV) may cause severe congenital disease after maternal–fetal
transmission. No vaccine is currently available. Objective: To assess the safety and …

Flavivirus infection—A review of immunopathogenesis, immunological response, and immunodiagnosis

HY Chong, CY Leow, ABA Majeed, CH Leow - Virus research, 2019 - Elsevier
Flaviviruses are group of single stranded RNA viruses that cause severe endemic infection
and epidemics on a global scale. It presents a significant health impact worldwide and the …

[HTML][HTML] Zika virus vaccines

P Abbink, KE Stephenson, DH Barouch - Nature Reviews Microbiology, 2018 - nature.com
The recent epidemic of Zika virus (ZIKV) in the Americas has revealed the devastating
consequences of ZIKV infection, particularly in pregnant women. Congenital Zika syndrome …

A recombinant platform for flavivirus vaccines and diagnostics using chimeras of a new insect-specific virus

J Hobson-Peters, JJ Harrison, D Watterson… - Science translational …, 2019 - science.org
Flaviviruses such as dengue, yellow fever, Zika, West Nile, and Japanese encephalitis virus
present substantial global health burdens. New vaccines are being sought to address safety …

Drugs for the treatment of Zika virus infection

JA Bernatchez, LT Tran, J Li, Y Luan… - Journal of medicinal …, 2019 - ACS Publications
Zika virus is an emerging flavivirus that causes the neurodevelopmental congenital Zika
syndrome and that has been linked to the neuroinflammatory Guillain–Barré syndrome. The …