Grafting modification of okra mucilage: Recent findings, applications, and future directions

V Raj, JJ Shim, J Lee - Carbohydrate polymers, 2020 - Elsevier
Okra polysaccharides are biocompatible polymers with antimicrobial, anticancer,
hypoglycemic, and antioxidant characteristics and hence are used in different fields such as …

Optimization of process parameters for fabrication of electrospun nanofibers containing neomycin sulfate and Malva sylvestris extract for a better diabetic wound …

M Monirul Islam, V HR, P Durga Bhavani… - Drug Delivery, 2022 - Taylor & Francis
Diabetes mellitus is one of the most concerning conditions, and its chronic consequences
are almost always accompanied by infection, oxidative stress, and inflammation. Reducing …

In situ gel loaded with chitosan-coated simvastatin nanoparticles: Promising delivery for effective anti-proliferative activity against tongue carcinoma

M Kurakula, NR Naveen - Marine Drugs, 2020 - mdpi.com
The goal of this study is to develop optimized chitosan-coated Simvastatin (SIM)
nanoparticles (NPs) loaded in an in situ gel (ISG) formulation via a face-centered central …

Process optimization by response surface methodology for preparation and evaluation of methotrexate loaded chitosan nanoparticles

NR Naveen, M Kurakula, B Gowthami - Materials Today: Proceedings, 2020 - Elsevier
Abstract Formulation optimization is a critical process in the development of nanoparticles to
apprehend the formulation variables and associated quality attributes. Nanoparticles …

Design and development of neomycin sulfate gel loaded with solid lipid nanoparticles for buccal mucosal wound healing

KM Hosny, NR Naveen, M Kurakula, AM Sindi… - Gels, 2022 - mdpi.com
Drug administration to the wound site is a potential method for wound healing. The drug
retention duration should be extended, and drug permeability through the buccal mucosal …

Preparation, optimization and evaluation of chitosan-based avanafil nanocomplex utilizing antioxidants for enhanced neuroprotective effect on PC12 cells

M Kurakula, R Naveen N, B Patel, R Manne, DB Patel - Gels, 2021 - mdpi.com
(1) Introduction: in recent decades, interdisciplinary research on the utilization of natural
products as “active moiety carriers” was focused on due to their superior safety profile …

Compression-coated pulsatile chronomodulated therapeutic system: QbD assisted optimization

HM Aldawsari, NR Naveen, NA Alhakamy… - Drug Delivery, 2022 - Taylor & Francis
Pulsatile drug delivery systems have drawn attention in contemporary research for
designing chronotherapeutic systems. The current work aims to design pulsatile ketorolac …

QbD supported optimization of the alginate-chitosan nanoparticles of simvastatin in enhancing the anti-proliferative activity against tongue carcinoma

WY Rizg, NR Naveen, M Kurakula, HA Bukhary… - Gels, 2022 - mdpi.com
The goal of the current study is to develop a chitosan alginate nanoparticle system
encapsulating the model drug, simvastatin (SIM-CA-NP) using a novel polyelectrolytic …

Response surface methodology (RSM) powered formulation development, optimization and evaluation of thiolated based mucoadhesive nanocrystals for local …

RB Bakhaidar, NR Naveen, P Basim, SS Murshid… - Polymers, 2022 - mdpi.com
In oral administration systems, mucoadhesive polymers are crucial for drug localization and
target-specific activities. The current work focuses on the application of thiolated xanthan …

Okra-Thioglycolic acid conjugate—Synthesis, characterization, and evaluation as a mucoadhesive polymer

NR Naveen, C Gopinath, M Kurakula - Processes, 2020 - mdpi.com
The success of mucoadhesive drug delivery systems relies on the type of polymer used,
which becomes adhesive naturally upon hydration. Intended polymers should be able to …