AI has seen wide adoption for automating tasks in several domains. However, AI's use in
high-value, sensitive, or safety-critical applications such as self-management for …

To elucidate the relationship between age and cognitive decline, it is important to consider
structural brain changes such as white matter hyperintensities (WMHs), which are common …

Background Premature age-related brain changes may be influenced by physical health
factors. Lower socioeconomic status (SES) is often associated with poorer physical health. In …

Prolonged periods of social isolation are known to have significant negative health
consequences and reduce quality of life, an effect that is particularly pronounced in older …

Premature brain aging is associated with poorer cognitive reserve and lower resilience to
injury. When there are focal brain lesions, brain regions may age at different rates within the …

Background: Brain age is an MRI-derived estimate of brain tissue loss that has a similar
pattern to aging-related atrophy. White matter hyperintensities (WMHs) are neuroimaging …

Background Cognitive impairment has multiple risk factors spanning several domains, but
few studies have evaluated risk factor clusters. We aimed to identify naturally occurring …

Abstract Background and Purpose Cerebral hypoperfusion has been described in both
severe and mild forms of symptomatic Coronavirus Disease 2019 (COVID‐19) infection. The …

In recent years, the relationship between age-related hearing loss, cognitive decline, and
the risk of dementia has garnered significant attention. The significant variability in brain …

Chronic stroke results in significant downstream changes at connected cortical sites.
However, less is known about the impact of cortical stroke on cerebellar structure. Here, we …