Mitotic spindle assembly in animal cells: a fine balancing act

SL Prosser, L Pelletier - Nature Reviews Molecular Cell Biology, 2017 - nature.com
The mitotic spindle has a crucial role in ensuring the accurate segregation of chromosomes
into the two daughter cells during cell division, which is paramount for maintaining genome …

Mechanisms underlying spindle assembly and robustness

VA Valdez, L Neahring, S Petry… - Nature Reviews Molecular …, 2023 - nature.com
The microtubule-based spindle orchestrates chromosome segregation during cell division.
Following more than a century of study, many components and pathways contributing to …

Mechanisms of chromosome congression during mitosis

H Maiato, AM Gomes, F Sousa, M Barisic - Biology, 2017 - mdpi.com
Chromosome congression during prometaphase culminates with the establishment of a
metaphase plate, a hallmark of mitosis in metazoans. Classical views resulting from more …

Mitotic spindle multipolarity without centrosome amplification

H Maiato, E Logarinho - Nature cell biology, 2014 - nature.com
Mitotic spindle bipolarity is essential for faithful segregation of chromosomes during cell
division. Multipolar spindles are often seen in human cancers and are usually associated …

[HTML][HTML] An anaphase surveillance mechanism prevents micronuclei formation from frequent chromosome segregation errors

B Orr, F De Sousa, AM Gomes, O Afonso, LT Ferreira… - Cell Reports, 2021 - cell.com
Micronuclei are a hallmark of cancer and several other human disorders. Recently,
micronuclei were implicated in chromothripsis, a series of massive genomic rearrangements …

Microtubule nucleation for spindle assembly: one molecule at a time

J Kraus, R Alfaro-Aco, B Gouveia, S Petry - Trends in biochemical sciences, 2023 - cell.com
The cell orchestrates the dance of chromosome segregation with remarkable speed and
fidelity. The mitotic spindle is built from scratch after interphase through microtubule (MT) …

Human centrosome organization and function in interphase and mitosis

A Vasquez-Limeta, J Loncarek - Seminars in cell & developmental biology, 2021 - Elsevier
Centrosomes were first described by Edouard Van Beneden and named and linked to
chromosome segregation by Theodor Boveri around 1870. In the 1960–1980s, electron …

The effect of corporate governance and audit quality on disclosure quality: Evidence from Tehran stock exchange

M Salehi, M Moradi, N Paiydarmanesh - Periodica Polytechnica Social …, 2017 - pp.bme.hu
The current study examines the effect of audit quality and internal and external corporate
governance on the quality of disclosure of financial statements. In order to achieving the …

Centrosomal and Non-Centrosomal Microtubule-Organizing Centers (MTOCs) in Drosophila melanogaster

MML Tillery, C Blake-Hedges, Y Zheng, RA Buchwalter… - Cells, 2018 - mdpi.com
The centrosome is the best-understood microtubule-organizing center (MTOC) and is
essential in particular cell types and at specific stages during Drosophila development. The …

Augmin-dependent microtubule self-organization drives kinetochore fiber maturation in mammals

AC Almeida, J Soares-de-Oliveira, D Drpic… - Cell Reports, 2022 - cell.com
Chromosome segregation in mammals relies on the maturation of a thick bundle of
kinetochore-attached microtubules known as k-fiber. How k-fibers mature from initial …