Mitotic spindle assembly in animal cells: a fine balancing act
SL Prosser, L Pelletier - Nature Reviews Molecular Cell Biology, 2017 - nature.com
The mitotic spindle has a crucial role in ensuring the accurate segregation of chromosomes
into the two daughter cells during cell division, which is paramount for maintaining genome …
into the two daughter cells during cell division, which is paramount for maintaining genome …
Mechanisms underlying spindle assembly and robustness
The microtubule-based spindle orchestrates chromosome segregation during cell division.
Following more than a century of study, many components and pathways contributing to …
Following more than a century of study, many components and pathways contributing to …
Mechanisms of chromosome congression during mitosis
Chromosome congression during prometaphase culminates with the establishment of a
metaphase plate, a hallmark of mitosis in metazoans. Classical views resulting from more …
metaphase plate, a hallmark of mitosis in metazoans. Classical views resulting from more …
Mitotic spindle multipolarity without centrosome amplification
H Maiato, E Logarinho - Nature cell biology, 2014 - nature.com
Mitotic spindle bipolarity is essential for faithful segregation of chromosomes during cell
division. Multipolar spindles are often seen in human cancers and are usually associated …
division. Multipolar spindles are often seen in human cancers and are usually associated …
[HTML][HTML] An anaphase surveillance mechanism prevents micronuclei formation from frequent chromosome segregation errors
B Orr, F De Sousa, AM Gomes, O Afonso, LT Ferreira… - Cell Reports, 2021 - cell.com
Micronuclei are a hallmark of cancer and several other human disorders. Recently,
micronuclei were implicated in chromothripsis, a series of massive genomic rearrangements …
micronuclei were implicated in chromothripsis, a series of massive genomic rearrangements …
Microtubule nucleation for spindle assembly: one molecule at a time
The cell orchestrates the dance of chromosome segregation with remarkable speed and
fidelity. The mitotic spindle is built from scratch after interphase through microtubule (MT) …
fidelity. The mitotic spindle is built from scratch after interphase through microtubule (MT) …
Human centrosome organization and function in interphase and mitosis
A Vasquez-Limeta, J Loncarek - Seminars in cell & developmental biology, 2021 - Elsevier
Centrosomes were first described by Edouard Van Beneden and named and linked to
chromosome segregation by Theodor Boveri around 1870. In the 1960–1980s, electron …
chromosome segregation by Theodor Boveri around 1870. In the 1960–1980s, electron …
The effect of corporate governance and audit quality on disclosure quality: Evidence from Tehran stock exchange
The current study examines the effect of audit quality and internal and external corporate
governance on the quality of disclosure of financial statements. In order to achieving the …
governance on the quality of disclosure of financial statements. In order to achieving the …
Centrosomal and Non-Centrosomal Microtubule-Organizing Centers (MTOCs) in Drosophila melanogaster
MML Tillery, C Blake-Hedges, Y Zheng, RA Buchwalter… - Cells, 2018 - mdpi.com
The centrosome is the best-understood microtubule-organizing center (MTOC) and is
essential in particular cell types and at specific stages during Drosophila development. The …
essential in particular cell types and at specific stages during Drosophila development. The …
Augmin-dependent microtubule self-organization drives kinetochore fiber maturation in mammals
AC Almeida, J Soares-de-Oliveira, D Drpic… - Cell Reports, 2022 - cell.com
Chromosome segregation in mammals relies on the maturation of a thick bundle of
kinetochore-attached microtubules known as k-fiber. How k-fibers mature from initial …
kinetochore-attached microtubules known as k-fiber. How k-fibers mature from initial …