Small dataset solves big problem: An outlier-insensitive binary classifier for inhibitory potency prediction
Nicotinamide phosphoribosyltransferase (NAMPT) inhibitors show importance in cancer
disease treatment while selecting compounds from a library according to inhibitory potency …
disease treatment while selecting compounds from a library according to inhibitory potency …
A multi-view multi-omics model for cancer drug response prediction
Cancer drug response prediction is the fundamental task in precision medicine, which
provides opportunities for cancer therapy. Several methods have been proposed to screen …
provides opportunities for cancer therapy. Several methods have been proposed to screen …
Integrating Multi-Omics Using Bayesian Ridge Regression with Iterative Similarity Bagging
TM Almutiri, KH Alomar, NA Alganmi - Applied Sciences, 2024 - mdpi.com
Cancer research has increasingly utilized multi-omics analysis in recent decades to obtain
biomolecular information from multiple layers, thereby gaining a better understanding of …
biomolecular information from multiple layers, thereby gaining a better understanding of …
Interval type-2 enhanced possibilistic fuzzy c-means clustering for gene expression data analysis
S Sotudian, MHF Zarandi - arXiv preprint arXiv:2101.00304, 2021 - arxiv.org
Both FCM and PCM clustering methods have been widely applied to pattern recognition and
data clustering. Nevertheless, FCM is sensitive to noise and PCM occasionally generates …
data clustering. Nevertheless, FCM is sensitive to noise and PCM occasionally generates …
Multi-Cohort Transcriptomic Profiling of Medical Gas Plasma-Treated Cancers Reveals the Role of Immunogenic Cell Death
A Gkantaras, C Kotzamanidis, K Kyriakidis, E Farmaki… - Cancers, 2024 - mdpi.com
Simple Summary Medical gas plasma is a new modality in cancer treatment showing
favorable results in preclinical and clinical trials; however, the cascade of molecular events …
favorable results in preclinical and clinical trials; however, the cascade of molecular events …
SAFE-MIL: a statistically interpretable framework for screening potential targeted therapy patients based on risk estimation
Y Guan, Z Xue, J Wang, X Ai, R Chen, X Yi, S Lu… - Frontiers in …, 2024 - frontiersin.org
Patients with the target gene mutation frequently derive significant clinical benefits from
target therapy. However, differences in the abundance level of mutations among patients …
target therapy. However, differences in the abundance level of mutations among patients …
Distributionally robust learning-to-rank under the Wasserstein metric
S Sotudian, R Chen, IC Paschalidis - PloS one, 2023 - journals.plos.org
Despite their satisfactory performance, most existing listwise Learning-To-Rank (LTR)
models do not consider the crucial issue of robustness. A data set can be contaminated in …
models do not consider the crucial issue of robustness. A data set can be contaminated in …
Social determinants of health and the prediction of missed breast imaging appointments
S Sotudian, A Afran, CA LeBedis, AF Rives… - BMC Health Services …, 2022 - Springer
Background Predictive models utilizing social determinants of health (SDH), demographic
data, and local weather data were trained to predict missed imaging appointments (MIA) …
data, and local weather data were trained to predict missed imaging appointments (MIA) …
ITNR: Inversion Transformer-based Neural Ranking for cancer drug recommendations
S Sotudian, IC Paschalidis - Computers in Biology and Medicine, 2024 - Elsevier
Personalized drug response prediction is an approach for tailoring effective therapeutic
strategies for patients based on their tumors' genomic characterization. While machine …
strategies for patients based on their tumors' genomic characterization. While machine …
Distributionally robust multi-output regression ranking
S Sotudian, R Chen, I Paschalidis - arXiv preprint arXiv:2109.12803, 2021 - arxiv.org
Despite their empirical success, most existing listwiselearning-to-rank (LTR) models are not
built to be robust to errors in labeling or annotation, distributional data shift, or adversarial …
built to be robust to errors in labeling or annotation, distributional data shift, or adversarial …