Nanotechnologies for control of pathogenic microbial biofilms

EO Asare, EA Mun, E Marsili, VN Paunov - Journal of Materials …, 2022 - pubs.rsc.org
Biofilms are formed at interfaces by microorganisms, which congregate in microstructured
communities embedded in a self-produced extracellular polymeric substance (EPS). Biofilm …

Beyond silver sulfadiazine: A dive into more than 50 years of research and development on metal complexes of sulfonamides in medicinal inorganic chemistry

JHB Nunes, DH Nakahata, PP Corbi… - Coordination Chemistry …, 2023 - Elsevier
Sulfonamides revolutionized the treatment and management of bacterial infections. Prontosil
was the very first synthetic antibacterial agent ever used in the clinics and its metabolite …

Metal Complexes as Antifungals? From a Crowd-Sourced Compound Library to the First In Vivo Experiments

A Frei, AG Elliott, A Kan, H Dinh, S Bräse, AE Bruce… - JACS au, 2022 - ACS Publications
There are currently fewer than 10 antifungal drugs in clinical development, but new fungal
strains that are resistant to most current antifungals are spreading rapidly across the world …

Targeting S. epidermidis Biofilms by the Tetracycline-Loaded Nanogel Surface Functionalized with Savinase, DNase, and Cellulase

EO Asare, A Seidakhanova… - ACS Applied Nano …, 2023 - ACS Publications
Persistent bacterial infections are causing millions of premature deaths worldwide due to
antimicrobial resistance and biofilm formation capabilities. Among these bacteria is …

Synthesis, crystal structures and CT-DNA/BSA binding properties of Co (III) and Cu (II) complexes with bipyridine Schiff base ligand

L Chang, J Yang, S Lai, X Liu, Z Yang, S Zhao - Inorganica Chimica Acta, 2022 - Elsevier
A novel bipyridine Schiff base ligand C 12 H 9 ClN 4 O (HL) and its two transition metal
complexes [CoL 2] NO 3⋅ H 2 O (1) and CuL 2⋅ CH 3 OH (2) have been synthesized. Their …

Silver (I) complexes containing antifungal azoles: significant improvement of the anti-Candida potential of the azole drug after its coordination to the silver (I) ion

M Stanković, J Kljun, NL Stevanović, J Lazic… - Dalton …, 2024 - pubs.rsc.org
Inspired by the emergence of resistance to currently available antifungal therapy and by the
great potential of metal complexes for the treatment of various diseases, we synthesized …

Three water-soluble acylhydrazone tetranuclear transition metal complexes: Crystal structures, DNA/BSA interactions and cytotoxicity studies

J Yang, G Liao, X Liu, S Zhao, Z Yang - Journal of Inorganic Biochemistry, 2022 - Elsevier
acetylpyridine-4-chloropyridine-2‑carbonyl hydrazone (C 13 H 11 ClN 4 O, HL) and its three
water-soluble tetranuclear complexes [Cu 4 (NO 3) 2 (L) 4]·(NO 3) 2 (1),[Co 4 (NO 3) 2 (H 2 …

Electroanalysis of Candida albicans biofilms: A suitable real-time tool for antifungal testing

K Olaifa, J Nikodinovic-Runic, B Glišić, F Boschetto… - Electrochimica …, 2021 - Elsevier
Candida albicans is a fungal pathogen that accounts for more than a million death annually.
Analysis of Candida biofilms and rapid assessment of antifungal therapy is a critical …

Purpose-built multicomponent supramolecular silver (i)-hydrogels as membrane-targeting broad-spectrum antibacterial agents against multidrug-resistant pathogens

E Saha, A Khan, AI Mallick, J Mitra - Journal of Materials Chemistry B, 2024 - pubs.rsc.org
Membrane-targeting compounds are of immense interest to counter complicated multi-drug
resistant infections. However, the broad-spectrum effect of such compounds is often unmet …

Cytotoxicity and antibacterial activity of silver complexes bearing semicarbazones and triphenylphosphine

VYG Almeida, JS Rocha, DP Felix, GP Oliveira… - …, 2020 - Wiley Online Library
The present work aimed to evaluate the biological activities of the silver (I) complexes, with
the formulae [Ag (L)(PPh3) 2]+ and [Ag (L) 2]+(L=(E)‐2‐((E)‐3‐phenylallylidene) hydrazine …