Krüppel-like factors are members of the zinc finger family of transcription factors that have
been implicated as playing key roles in regulating cellular differentiation and tissue …

Recent advances in molecular cloning have led to the identification of a large number of
mammalian zinc finger-containing transcription factors that exhibit homology to the …

Marbling influences the taste and tenderness of meat and is the main determinant of carcass
quality in many countries. This study aims to investigate the influence of KLF6 (Kruppel Like …

Kruppel-like factor 6 (KLF6) is a zinc finger transcription factor of unknown function. Here, we
show that the KLF6 gene is mutated in a subset of human prostate cancer. Loss-of …

Hepatic fibrosis is a wound‐healing response to chronic liver injury, which if persistent leads
to cirrhosis and liver failure. Exciting progress has been made in understanding the …

One of the most common regulatory elements is the GC box and the related GT/CACC box,
which are widely distributed in promoters, enhancers and locus control regions of …

Krüppel-like factors (KLFs) are a family of zinc-finger transcription factors that are found in
many species. Recent studies have shown that KLFs play a fundamental role in regulating …

The transcription factor SP1 contains three Krüppel-like zinc fingers. Recently, several
related proteins, including erythroid, lung and gut-enriched Krüppel-like factors, have been …

Wound repair in the liver induces altered gene expression in stellate cells (resident
mesenchymal cells) in a process known as “activation.” A zinc finger transcription factor …

T has been exciting progress in our understand-ing of hepatic fibrosis in the past
decade. Hepatic fibrosis, or the deposition of extracellular matrix, was once viewed as a …