This critical review provides an overview of the continually expanding family of fluorescent
proteins (FPs) that have become essential tools for studies of cell biology and physiology …

Since its first splash 30 years ago, the use of the zebrafish model has been extended from a
tool for genetic dissection of early vertebrate development to the functional interrogation of …

The adult zebrafish heart has a high capacity for regeneration following injury. However, the
composition of the regenerative niche has remained largely elusive. Here, we dissected the …

Wound angiogenesis is an integral part of tissue repair and is impaired in many pathologies
of healing. Here, we investigate the cellular interactions between innate immune cells and …

For an epithelium to provide a protective barrier, it must maintain homeostatic cell numbers
by matching the number of dividing cells with the number of dying cells. Although …

Understanding the principles of information processing in neural circuits requires systematic
characterization of the participating cell types and their connections, and the ability to …

Adult neurogenesis is a widespread trait of vertebrates; however, the degree of this ability
and the underlying activity of the adult neural stem cells differ vastly among species. In …

Targeted gene expression is a powerful approach to study the function of genes and cells in
vivo. In Drosophila, the P element-mediated Gal4-UAS method has been successfully used …

Most vertebrates process visual information using elaborately structured photosensory
tissues, including the eyes and pineal. However, there is strong evidence that other tissues …

Macrophages are essential for appendage regeneration after amputation in regenerative
species. The molecular mechanisms through which macrophages orchestrate blastema …