Multiple laser Doppler flowmetry probes increase the reproducibility of skin blood flow measurements

JC Luck, AR Kunselman, MD Herr, CA Blaha… - Frontiers in …, 2022 - frontiersin.org
Cutaneous microcirculatory perfusion is commonly measured using laser Doppler flowmetry
(LDF) probes, which provide a continuous, non-invasive quantification of skin blood flow …

A spike in circulating cytokines TNF-α and TGF-β alters barrier function between vascular and musculoskeletal tissues

L Ngo, ML Knothe Tate - Scientific Reports, 2023 - nature.com
Molecular transport between the circulatory and musculoskeletal systems regulates articular
joint physiology in health and disease. Osteoarthritis (OA) is a degenerative joint disease …

Automatic correction of motion artifact in dynamic contrast-enhanced fluorescence imaging during open orthopedic surgery

Y Tang, IL Gitajn, X Cao, X Han… - Journal of …, 2024 - spiedigitallibrary.org
Significance Indocyanine green-based dynamic contrast-enhanced fluorescence imaging
(DCE-FI) can objectively assess bone perfusion intraoperatively. However, it is susceptible …

Femoral skeletal perfusion is reduced in male mice with Type 1 diabetes

S Ucer Ozgurel, EA Swallow, CE Metzger… - Calcified Tissue …, 2022 - Springer
The bone vasculature and blood flow are critical for bone modeling, remodeling, and
regeneration. Vascular complications are one of the major health concerns of people with …

[HTML][HTML] A minimally invasive technique for serial intraosseous perfusion measurements in the murine tibia using laser Doppler flowmetry

NJ Hanne, ED Easter, S Stangeland-Molo, JH Cole - MethodsX, 2020 - Elsevier
In biomedical and preclinical research, the current standard method for measuring blood
perfusion inside murine bone, radiolabeled microspheres, is a terminal procedure that …

Ischemic stroke reduces bone perfusion and alters osteovascular structure

NJ Hanne, AJ Steward, C Geeroms, ED Easter… - BioRxiv, 2019 - biorxiv.org
Rationale Stroke patients lose bone mass and experience fracture at an elevated rate.
Although functional intraosseous vasculature is necessary for skeletal maintenance, the …

High fat diet-induced obesity negatively affects whole bone bending strength but not cortical structure in the femur

NJ Hanne, AJ Steward, JM Cox, ED Easter… - BioRxiv, 2019 - biorxiv.org
Although body mass index is positively associated with bone mineral density, suggesting
obesity is protective against fracture, elderly obese individuals experience greater fracture …