Neutrophil extracellular traps participate in cardiovascular diseases: recent experimental and clinical insights

Y Döring, P Libby, O Soehnlein - Circulation research, 2020 - Am Heart Assoc
Neutrophil extracellular traps (NETs) have recently emerged as a newly recognized
contributor to venous and arterial thrombosis. These strands of DNA extruded by activated or …

Liquid biopsies: genotyping circulating tumor DNA

LA Diaz Jr, A Bardelli - Journal of clinical oncology, 2014 - ascopubs.org
Genotyping tumor tissue in search of somatic genetic alterations for actionable information
has become routine practice in clinical oncology. Although these sequence alterations are …

Circulating cell free DNA: preanalytical considerations

S El Messaoudi, F Rolet, F Mouliere, AR Thierry - Clinica chimica acta, 2013 - Elsevier
Despite the growing interest in circulating cell-free DNA (ccfDNA) analysis in various clinical
fields, especially oncology and prenatal diagnosis, few studies on sample handling have …

Oxidative stress markers among obstructive sleep apnea patients

A Stanek, K Brożyna-Tkaczyk… - Oxidative Medicine and …, 2021 - Wiley Online Library
Obstructive sleep apnea (OSA) is a chronic respiratory disorder, which can be present in up
to 50% of the population, depending on the country. OSA is characterized by recurrent …

Elevated levels of circulating DNA in cardiovascular disease patients: metagenomic profiling of microbiome in the circulation

V Dinakaran, A Rathinavel, M Pushpanathan… - PloS one, 2014 - journals.plos.org
Cardiovascular diseases (CVDs) are the leading cause of death worldwide. An expanding
body of evidence supports the role of human microbiome in the establishment of CVDs and …

NETosis promotes cancer-associated arterial microthrombosis presenting as ischemic stroke with troponin elevation

C Thålin, M Demers, B Blomgren, SL Wong… - Thrombosis research, 2016 - Elsevier
Introduction Large elevations of high sensitive Troponin T (hsTnT) in ischemic stroke
patients is associated with a poor outcome. In a pilot study we found a high prevalence of …

[HTML][HTML] The pathophysiological role of neutrophil extracellular traps in inflammatory diseases

A Bonaventura, L Liberale, F Carbone… - Thrombosis and …, 2018 - thieme-connect.com
Neutrophil pathogen-killing mechanism termed neutrophil extracellular traps (NETs) has
been recently identified. NETs consist of chromatin and histones along with serine proteases …

Plasma myeloperoxidase-conjugated DNA level predicts outcomes and organ dysfunction in patients with septic shock

Y Maruchi, M Tsuda, H Mori, N Takenaka, T Gocho… - Critical care, 2018 - Springer
Background Recent studies have suggested that excessive formation of neutrophil
extracellular traps (NETs) plays a critical role in the pathogenesis of sepsis. Although …

Neutrophil extracellular traps and fibrocytes in ST-segment elevation myocardial infarction

TM Hofbauer, A Mangold, T Scherz, V Seidl… - Basic research in …, 2019 - Springer
Leukocyte-mediated inflammation is central in atherothrombosis and ST-segment elevation
myocardial infarction (STEMI). Neutrophil extracellular traps (NETs) have been shown to …

Cell free DNA as a diagnostic and prognostic marker for cardiovascular diseases

IA Polina, DV Ilatovskaya, KY DeLeon-Pennell - Clinica Chimica Acta, 2020 - Elsevier
Release of cell free DNA (cfDNA) from damaged or dead cells routinely occurs in normal
physiology. Recently, cfDNA has emerged as an essential biomarker in cardiovascular …