Human herpesviruses 6A and 6B in brain diseases: association versus causation

AL Komaroff, PE Pellett, S Jacobson - Clinical microbiology …, 2020 - Am Soc Microbiol
SUMMARY Human herpesvirus 6A (HHV-6A) and human herpesvirus 6B (HHV-6B),
collectively termed HHV-6A/B, are neurotropic viruses that permanently infect most humans …

Current understanding of human herpesvirus 6 (HHV-6) chromosomal integration

G Aimola, G Beythien, A Aswad, BB Kaufer - Antiviral research, 2020 - Elsevier
Abstract Human herpesvirus 6A (HHV-6A) and 6B (HHV–6B) are members of the genus
Roseolovirus in the Betaherpesvirinae subfamily. HHV-6B infects humans in the first years of …

Evolutionary history of endogenous human herpesvirus 6 reflects human migration out of Africa

A Aswad, G Aimola, D Wight… - Molecular Biology …, 2021 - academic.oup.com
Human herpesvirus 6A and 6B (HHV-6) can integrate into the germline, and as a result,∼
70 million people harbor the genome of one of these viruses in every cell of their body. Until …

Comparative analysis of roseoloviruses in humans, pigs, mice, and other species

J Denner, TM Bigley, TL Phan, C Zimmermann, X Zhou… - Viruses, 2019 - mdpi.com
Viruses of the genus Roseolovirus belong to the subfamily Betaherpesvirinae, family
Herpesviridae. Roseoloviruses have been studied in humans, mice and pigs, but they are …

[HTML][HTML] Respiratory viruses and febrile response in children with febrile seizures: a cohort study and embedded case-control study

M Hautala, J Arvila, T Pokka, K Mikkonen, U Koskela… - Seizure, 2021 - Elsevier
Objective There are limited data on the pathogen-related and host-related factors in the
pathogenesis of febrile seizures (FS). We designed a controlled study to compare the role of …

[HTML][HTML] The viral hypothesis of mesial temporal lobe epilepsy–is human herpes virus-6 the missing link? A systematic review and meta-analysis

P Wipfler, N Dunn, O Beiki, E Trinka, A Fogdell-Hahn - Seizure, 2018 - Elsevier
Purpose Mesial temporal lobe epilepsy (MTLE) is a common epileptic disorder. Although
likely multifactorial, the mechanisms underlying the etiology and pathogenesis of the …

Infection with HHV-6 and its role in epilepsy

L Bartolini, WH Theodore, S Jacobson, WD Gaillard - Epilepsy research, 2019 - Elsevier
Abstract Infection with Human Herpesvirus-6 (HHV-6) has been associated with different
epilepsy syndromes, including febrile seizures and status epilepticus, acute symptomatic …

Febrile seizures and respiratory viruses determined by multiplex polymerase chain reaction test and clinical diagnosis

JY Han, SB Han - Children, 2020 - mdpi.com
Febrile seizure (FS) is a common benign seizure disorder of young children. Although upper
respiratory tract infection is the cause of fever in most episodes of FS, studies to identify …

Inherited Chromosomally Integrated Human Herpesvirus 6: Laboratory and Clinical Features

L Gabrielli, A Balboni, EC Borgatti, G Virgili, E Petrisli… - Microorganisms, 2023 - mdpi.com
Inherited chromosomally integrated human herpesvirus 6 (iciHHV-6) is a condition in which
the complete HHV-6 genome is integrated into the chromosomes of the host germ cell and is …

[HTML][HTML] Etiology of central nervous system infections in a rural area of Nepal using molecular approaches

O Säll, ST Hedberg, M Neander, S Tiwari… - The American Journal …, 2019 - ncbi.nlm.nih.gov
The etiology of infections of the central nervous system (CNS) in Nepal often remains
unrecognized because of underdeveloped laboratory facilities. The aim of this study was to …