Disclosing common biological signatures and predicting new therapeutic targets in schizophrenia and obsessive–compulsive disorder by integrated bioinformatics …

A Ghanbarzehi, A Sepehrinezhad, N Hashemi… - BMC psychiatry, 2023 - Springer
Schizophrenia (SCZ) is a severe mental illness mainly characterized by a number of
psychiatric symptoms. Obsessive–compulsive disorder (OCD) is a long-lasting and …

Bioinformatics analysis of miR-181a and its role in adipogenesis, obesity, and lipid metabolism through review of literature

G Hongfang, R Khan, AA El-Mansi - Molecular Biotechnology, 2024 - Springer
The miRNAs regulate various biological processes in the mammalian body system. The role
of miR-181a in the development, progression, and expansion of cancers is well …

Genetic determinants of coping, resilience and self-esteem in schizophrenia suggest a primary role for social factors and hippocampal neurogenesis

F Mazzarotto, P Monteleone, A Minelli, S Mattevi… - Psychiatry …, 2024 - Elsevier
Schizophrenia is a severe psychiatric disorder, associated with a reduction in life
expectancy of 15–20 years. Available treatments are at least partially effective in most …

The neurodevelopmental regulatory role and clinical value of hsa-circ-CORO1C–hsa-miR-708-3p–JARID2+ LNPEP axis in early-onset schizophrenia

Z Li, X Du, X Wang, J Hu, M Liu, Y Gao, Z Liu, X Cao… - Schizophrenia, 2024 - nature.com
Genes discovered by previous epigenetic studies of schizophrenia have focused solely on
diagnostics or pathology, potentially leading to a disconnection between them. Using these …

Alteration of microRNA expression in lymphocytes in patients with first-episode schizophrenia

X Wang - 2023 - researchsquare.com
Background The development of schizophrenia is related to a combination of genetic and
epigenomic factors. MicroRNAs (miRNAs) play a crucial role in epigenetic processes and …