Chemical fixation creates nanoscale clusters on the cell surface by aggregating membrane proteins
Chemical fixations have been thought to preserve the structures of the cells or tissues.
However, given that the fixatives create crosslinks or aggregate proteins, there is a …
However, given that the fixatives create crosslinks or aggregate proteins, there is a …
Formamide denaturation of double-stranded DNA for fluorescence in situ hybridization (FISH) distorts nanoscale chromatin structure
As imaging techniques rapidly evolve to probe nanoscale genome organization at higher
resolution, it is critical to consider how the reagents and procedures involved in sample …
resolution, it is critical to consider how the reagents and procedures involved in sample …
Multimodal interference-based imaging of nanoscale structure and macromolecular motion uncovers UV induced cellular paroxysm
Understanding the relationship between intracellular motion and macromolecular structure
remains a challenge in biology. Macromolecular structures are assembled from numerous …
remains a challenge in biology. Macromolecular structures are assembled from numerous …
Chromatin packing domains persist after RAD21 depletion in 3D.
WS Li, LM Carter, LM Almassalha, EM Pujadas-Liwag… - biorxiv, 2024 - biorxiv.org
Understanding chromatin organization requires integrating measurements of genome
connectivity and physical structure. Prior work demonstrates that RAD21 depletion results in …
connectivity and physical structure. Prior work demonstrates that RAD21 depletion results in …
Chromosome inner structure investigation by electron tomography and electron diffraction in a transmission electron microscope
R Phengchat, M Malac, M Hayashida - Chromosome Research, 2021 - Springer
Our understanding of the inner structure of metaphase chromosomes remains inconclusive
despite intensive studies using multiple imaging techniques. Transmission electron …
despite intensive studies using multiple imaging techniques. Transmission electron …
Multimodal interferometric imaging of nanoscale structure and macromolecular motion uncovers UV induced cellular paroxysm
We present a multimodal label-free interferometric imaging platform for measuring
intracellular nanoscale structure and macromolecular dynamics in living cells with a …
intracellular nanoscale structure and macromolecular dynamics in living cells with a …