The inositol pyrophosphate pathway in health and diseases

A Chakraborty - Biological Reviews, 2018 - Wiley Online Library
Inositol pyrophosphates (IPPs) are present in organisms ranging from plants, slime moulds
and fungi to mammals. Distinct classes of kinases generate different forms of energetic …

[HTML][HTML] Versatile signaling mechanisms of inositol pyrophosphates

MN Trung, D Furkert, D Fiedler - Current opinion in chemical biology, 2022 - Elsevier
Inositol pyrophosphates (PP-InsPs) constitute a group of highly charged messengers, which
regulate central biological processes in health and disease, such as cellular phosphate and …

Inositol Pyrophosphates as Versatile Metabolic Messengers

L Nagpal, S He, F Rao, SH Snyder - Annual review of …, 2024 - annualreviews.org
Discovered in 1993, inositol pyrophosphates are evolutionarily conserved signaling
metabolites whose versatile modes of action are being increasingly appreciated. These …

Cellular delivery and photochemical release of a caged inositol-pyrophosphate induces PH-domain translocation in cellulo

I Pavlovic, DT Thakor, JR Vargas, CJ McKinlay… - Nature …, 2016 - nature.com
Inositol pyrophosphates, such as diphospho-myo-inositol pentakisphosphates (InsP7), are
an important family of signalling molecules, implicated in many cellular processes and …

Inositol pyrophosphates: signaling molecules with pleiotropic actions in mammals

S Lee, MG Kim, H Ahn, S Kim - Molecules, 2020 - mdpi.com
Inositol pyrophosphates (PP-IPs) such as 5-diphosphoinositol pentakisphosphate (5-IP7)
are inositol metabolites containing high-energy phosphoanhydride bonds. Biosynthesis of …

[HTML][HTML] Inositol phosphate kinases in the eukaryote landscape

D Laha, P Portela-Torres, Y Desfougères… - Advances in biological …, 2021 - Elsevier
Inositol phosphate encompasses a large multifaceted family of signalling molecules that
originate from the combinatorial attachment of phosphate groups to the inositol ring. To date …

Lentinula edodes genome survey and postharvest transcriptome analysis

Y Sakamoto, K Nakade, S Sato, K Yoshida… - Applied and …, 2017 - Am Soc Microbiol
Lentinula edodes is a popular, cultivated edible and medicinal mushroom. Lentinula edodes
is susceptible to postharvest problems, such as gill browning, fruiting body softening, and …

The COP9 signalosome: A versatile regulatory hub of Cullin-RING ligases

E Schulze-Niemand, M Naumann - Trends in Biochemical Sciences, 2023 - cell.com
The COP9 signalosome (CSN) is a universal regulator of Cullin-RING ubiquitin ligases
(CRLs)–a family of modular enzymes that control various cellular processes via timely …

The emerging roles of inositol pyrophosphates in eukaryotic cell physiology

SG Thota, R Bhandari - Journal of biosciences, 2015 - Springer
Inositol pyrophosphates are water soluble derivatives of inositol that contain pyrophosphate
or diphosphate moieties in addition to monophosphates. The best characterised inositol …

Inositol hexakisphosphate kinases differentially regulate trafficking of vesicular glutamate transporters 1 and 2

H Li, M Datunashvili, RC Reyes… - Frontiers in Cellular …, 2022 - frontiersin.org
Inositol pyrophosphates have been implicated in cellular signaling and membrane
trafficking, including synaptic vesicle (SV) recycling. Inositol hexakisphosphate kinases …