Pathophysiology of chronic graft-versus-host disease and therapeutic targets
Chronic GVHD, an autoimmune disease that follows allogeneic hematopoietic-cell
transplantation, is characterized by infections and debilitating tissue injury leading to …
transplantation, is characterized by infections and debilitating tissue injury leading to …
[HTML][HTML] The biology of chronic graft-versus-host disease: a task force report from the National Institutes of Health Consensus Development Project on Criteria for …
KR Cooke, L Luznik, S Sarantopoulos, FT Hakim… - Biology of Blood and …, 2017 - Elsevier
Chronic graft-versus-host disease (GVHD) is the leading cause of late, nonrelapse mortality
and disability in allogeneic hematopoietic cell transplantation recipients and a major …
and disability in allogeneic hematopoietic cell transplantation recipients and a major …
Ibrutinib for chronic graft-versus-host disease after failure of prior therapy
Chronic graft-versus-host disease (cGVHD) is a serious complication of allogeneic stem cell
transplantation with few effective options available after failure of corticosteroids. B and T …
transplantation with few effective options available after failure of corticosteroids. B and T …
Chronic graft-versus-host disease: biological insights from preclinical and clinical studies
KPA MacDonald, GR Hill… - Blood, The Journal of the …, 2017 - ashpublications.org
With the increasing use of mismatched, unrelated, and granulocyte colony-stimulating factor–
mobilized peripheral blood stem cell donor grafts and successful treatment of older …
mobilized peripheral blood stem cell donor grafts and successful treatment of older …
Current issues in chronic graft-versus-host disease
Chronic graft-versus-host disease (GVHD) is a frequent and potentially life-threatening
complication of allogeneic hematopoietic stem cell transplantation. Increased …
complication of allogeneic hematopoietic stem cell transplantation. Increased …
Ibrutinib treatment ameliorates murine chronic graft-versus-host disease
JA Dubovsky, R Flynn, J Du… - The Journal of …, 2014 - Am Soc Clin Investig
Chronic graft-versus-host disease (cGVHD) is a life-threatening impediment to allogeneic
hematopoietic stem cell transplantation, and current therapies do not completely prevent …
hematopoietic stem cell transplantation, and current therapies do not completely prevent …
Donor B-cell alloantibody deposition and germinal center formation are required for the development of murine chronic GVHD and bronchiolitis obliterans
M Srinivasan, R Flynn, A Price… - Blood, The Journal …, 2012 - ashpublications.org
Chronic GVHD (cGVHD) poses a significant risk for HSCT patients. Preclinical development
of new therapeutic modalities has been hindered by models with pathologic findings that …
of new therapeutic modalities has been hindered by models with pathologic findings that …
Altered B-cell homeostasis and excess BAFF in human chronic graft-versus-host disease
Chronic graft-versus-host disease (cGVHD) causes significant morbidity and mortality in
patients otherwise cured of malignancy after hematopoietic stem cell transplantation …
patients otherwise cured of malignancy after hematopoietic stem cell transplantation …
Immune reconstitution after hematopoietic cell transplantation
Immune reconstitution after hematopoietic cell transplantati... : Current Opinion in
Hematology Immune reconstitution after hematopoietic cell transplantation : Current …
Hematology Immune reconstitution after hematopoietic cell transplantation : Current …
The role of B cells in the pathogenesis of graft-versus-host disease
A Shimabukuro-Vornhagen, MJ Hallek… - Blood, The Journal …, 2009 - ashpublications.org
Allogeneic hematopoietic stem cell transplantation is an established treatment modality for
malignant and nonmalignant hematologic diseases. Acute and chronic graft-versus-host …
malignant and nonmalignant hematologic diseases. Acute and chronic graft-versus-host …