The valproic acid-induced rodent model of autism

C Nicolini, M Fahnestock - Experimental neurology, 2018 - Elsevier
Autism is a lifelong neurodevelopmental disorder characterized by impairments in social
communication and interaction and by repetitive patterns of behavior, interests and activities …

Genetics and epigenetics of autism spectrum disorder—current evidence in the field

B Wiśniowiecka-Kowalnik, BA Nowakowska - Journal of applied genetics, 2019 - Springer
Autism spectrum disorders (ASD) is a heterogenous group of neurodevelopmental disorders
characterized by problems in social interaction and communication as well as the presence …

Interindividual methylomic variation across blood, cortex, and cerebellum: implications for epigenetic studies of neurological and neuropsychiatric phenotypes

E Hannon, K Lunnon, L Schalkwyk, J Mill - Epigenetics, 2015 - Taylor & Francis
Given the tissue-specific nature of epigenetic processes, the assessment of disease-relevant
tissue is an important consideration for epigenome-wide association studies (EWAS). Little …

Guidance for DNA methylation studies: statistical insights from the Illumina EPIC array

G Mansell, TJ Gorrie-Stone, Y Bao, M Kumari… - BMC genomics, 2019 - Springer
Background There has been a steady increase in the number of studies aiming to identify
DNA methylation differences associated with complex phenotypes. Many of the challenges …

Epigenomic signatures reveal mechanistic clues and predictive markers for autism spectrum disorder

JM LaSalle - Molecular psychiatry, 2023 - nature.com
Autism spectrum disorder (ASD) comprises a heterogeneous group of neurodevelopmental
outcomes in children with a commonality in deficits in social communication and language …

The PedBE clock accurately estimates DNA methylation age in pediatric buccal cells

LM McEwen, KJ O'Donnell, MG McGill… - Proceedings of the …, 2020 - National Acad Sciences
The development of biological markers of aging has primarily focused on adult samples.
Epigenetic clocks are a promising tool for measuring biological age that show impressive …

Environmental chemical exposures and autism spectrum disorders: a review of the epidemiological evidence

AE Kalkbrenner, RJ Schmidt, AC Penlesky - Current problems in pediatric …, 2014 - Elsevier
In the past decade, the number of epidemiological publications addressing environmental
chemical exposures and autism has grown tremendously. These studies are important …

DNA methylation biomarkers: cancer and beyond

T Mikeska, JM Craig - Genes, 2014 - mdpi.com
Biomarkers are naturally-occurring characteristics by which a particular pathological process
or disease can be identified or monitored. They can reflect past environmental exposures …

Epigenome-wide association studies and the interpretation of disease-omics

E Birney, GD Smith, JM Greally - PLoS genetics, 2016 - journals.plos.org
Epigenome-wide association studies represent one means of applying genome-wide
assays to identify molecular events that could be associated with human phenotypes. The …

The role of epigenetic change in autism spectrum disorders

YJ Loke, AJ Hannan, JM Craig - Frontiers in neurology, 2015 - frontiersin.org
Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental
disorders characterized by problems with social communication, social interaction, and …