Mutations in methyl CpG binding protein 2 (MeCP2) are the major cause of Rett syndrome
(RTT), a rare neurodevelopmental disorder with a notable period of developmental …

Rett Syndrome (RTT) is a severe, rare, and progressive developmental disorder with
patients displaying neurological regression and autism spectrum features. The affected …

MECP2 duplication syndrome (MDS) is a rare, X-linked, neurodevelopmental disorder
caused by a duplication of the methyl-CpG-binding protein 2 (MECP2) gene—a gene in …

DNA methylation, one of the most well-studied epigenetic modifications, is involved in a
wide spectrum of biological processes. Epigenetic mechanisms control cellular morphology …

Methyl-CpG-binding protein 2 (MeCP2) is a transcriptional regulator that is highly abundant
in the brain. It binds to methylated genomic DNA to regulate a range of physiological …

Rett Syndrome (RTT) is a rare and severe X-linked developmental brain disorder that occurs
primarily in females, with a ratio of 1: 10.000. De novo mutations in the Methyl-CpG Binding …

Methyl CpG binding protein 2 (MECP2) is located at Xq28 and is a multifunctional gene with
ubiquitous expression. Loss-of-function mutations in MECP2 are associated with Rett …

Rett Syndrome (RTT) is a rare and progressive neurodevelopmental disorder that is caused
by de novo mutations in the X-linked Methyl CpG binding protein 2 (MECP2) gene and is …

Eukaryotic gene expression is controlled at multiple steps that work in harmony to ensure
proper maintenance of cellular morphology and function. Such regulatory mechanisms …

MeCP2 protein, encoded by the MECP2 gene, binds to DNA and affects transcription.
Outside of this activity the true range of MeCP2 function is still not entirely clear. As MECP2 …