Metformin can suppress gluconeogenesis and reduce blood sugar by activating adenosine
monophosphate-activated protein kinase (AMPK) and inducing small heterodimer partner …

Atrial fibrillation/flutter (AF/AFL) is a common cardiac arrhythmia in patients with diabetes
and is associated with an increased risk of morbidity, including ischaemic stroke and heart …

Background and aim Stroke and cardiovascular diseases are major causes of death and
disability, especially among diabetic patients. Some studies have shown that metformin has …

Atrial fibrillation (AF) is the commonest sustained cardiac arrhythmia observed in clinical
practice. Its prevalence increases dramatically with advancing age. This review article …

Naturally occurring DNA gaps have been observed in eukaryotic DNA, including DNA in
nondividing cells. These DNA gaps are found less frequently in chronologically aging yeast …

Disorders in glucose metabolism can be divided into three separate but interrelated
domains, namely hyperglycemia, hypoglycemia, and glycemic variability. Intensive glycemic …

Background The long-term prognosis of the cardio-metabolic and renal complications, in
addition to mortality in patients with newly diagnosed pulmonary hypertension, are unclear …

Introduction Alu hypomethylation is a common epigenetic process that promotes genomic
instability with aging phenotypes, which leads to type 2 diabetes mellitus (type 2 DM) …

Abstract Background Type 2 diabetes (T2D) has a strong association with atrial fibrillation
(AF) which increases risk of thromboembolic events, heart failure, and frequent …

Background: Routinely collected health data are increasingly used in clinical research. No
study has systematically reviewed the temporal trends in the number of publications and …