Proteomics of human biological fluids for biomarker discoveries: technical advances and recent applications

L Dayon, O Cominetti, M Affolter - Expert review of proteomics, 2022 - Taylor & Francis
Introduction Biological fluids are routine samples for diagnostic testing and monitoring.
Blood samples are typically measured because of their moderate invasive collection and …

Quantitation in mass-spectrometry-based proteomics

WX Schulze, B Usadel - Annual review of plant biology, 2010 - annualreviews.org
Mass-spectrometry-based proteomics, the large-scale analysis of proteins by mass
spectrometry, has emerged as a new technology over the last decade and become routine …

A systematic evaluation of normalization methods in quantitative label-free proteomics

T Välikangas, T Suomi, LL Elo - Briefings in bioinformatics, 2018 - academic.oup.com
To date, mass spectrometry (MS) data remain inherently biased as a result of reasons
ranging from sample handling to differences caused by the instrumentation. Normalization is …

Comparative analysis of proteome and transcriptome variation in mouse

A Ghazalpour, B Bennett, VA Petyuk, L Orozco… - PLoS …, 2011 - journals.plos.org
The relationships between the levels of transcripts and the levels of the proteins they encode
have not been examined comprehensively in mammals, although previous work in plants …

Normalization and missing value imputation for label-free LC-MS analysis

YV Karpievitch, AR Dabney, RD Smith - BMC bioinformatics, 2012 - Springer
Shotgun proteomic data are affected by a variety of known and unknown systematic biases
as well as high proportions of missing values. Typically, normalization is performed in an …

Normalyzer: a tool for rapid evaluation of normalization methods for omics data sets

A Chawade, E Alexandersson… - Journal of proteome …, 2014 - ACS Publications
High-throughput omics data often contain systematic biases introduced during various steps
of sample processing and data generation. As the source of these biases is usually …

The pathogenesis and pathophysiology of gestational diabetes mellitus: Deductions from a three-part longitudinal metabolomics study in China

KP Law, H Zhang - Clinica Chimica Acta, 2017 - Elsevier
Gestational diabetes mellitus (GDM) is a form of diabetes that is first recognised during
pregnancy, with no evidence of pre-existing type 1 or type 2 diabetes. The prevalence of …

[HTML][HTML] Liquid chromatography mass spectrometry-based proteomics: biological and technological aspects

YV Karpievitch, AD Polpitiya, GA Anderson… - The annals of applied …, 2010 - ncbi.nlm.nih.gov
Mass spectrometry-based proteomics has become the tool of choice for identifying and
quantifying the proteome of an organism. Though recent years have seen a tremendous …

Pharmacometabonomics: data processing and statistical analysis

J Fu, Y Zhang, J Liu, X Lian, J Tang… - Briefings in …, 2021 - academic.oup.com
Individual variations in drug efficacy, side effects and adverse drug reactions are still
challenging that cannot be ignored in drug research and development. The aim of …

A comprehensive evaluation of popular proteomics software workflows for label-free proteome quantification and imputation

T Välikangas, T Suomi, LL Elo - Briefings in bioinformatics, 2018 - academic.oup.com
Label-free mass spectrometry (MS) has developed into an important tool applied in various
fields of biological and life sciences. Several software exist to process the raw MS data into …