3-Indolepropionic acid upturned male reproductive function by reducing oxido-inflammatory responses and apoptosis along the hypothalamic-pituitary-gonadal axis of …

SE Owumi, MT Otunla, UO Arunsi, ES Najophe - Toxicology, 2021 - Elsevier
We examined the effect of 3-Indolepropionic acid (3-IPA), an antioxidant on the
organophosphorus pesticide chlorpyrifos (CPF)-induced reproductive toxicity in rats. The …

Prenatal toxicity of the environmental pollutants on neuronal and cardiac development derived from embryonic stem cells

EB Ko, KA Hwang, KC Choi - Reproductive Toxicology, 2019 - Elsevier
Pesticides, antibiotics, and industrial excipients are widely used in agriculture, medicine,
and chemical industry, respectively. They often end up in the environment, not only being …

Differences in neurotoxic outcomes of organophosphorus pesticides revealed via multi-dimensional screening in adult and regenerating planarians

D Ireland, S Zhang, V Bochenek, JH Hsieh… - Frontiers in …, 2022 - frontiersin.org
Organophosphorus pesticides (OPs) are a chemically diverse class of commonly used
insecticides. Epidemiological studies suggest that low dose chronic prenatal and infant …

Obesogenic effects of chlorpyrifos and its metabolites during the differentiation of 3T3-L1 preadipocytes

J Blanco, L Guardia-Escote, M Mulero… - Food and Chemical …, 2020 - Elsevier
Chlorpyrifos (CPF) is an organophosphorus pesticide widely and extensively used in
agriculture in more than one hundred countries and found ubiquitously in the environment …

Impact of chlorpyrifos on human villous trophoblasts and chorionic villi

ME Ridano, AC Racca, JB Flores-Martin… - Toxicology and applied …, 2017 - Elsevier
Placental barrier regulates maternal-fetal interchange protecting the baby from damage
caused by substances found in the uterine environment or circulating in the vascular system …

Comparison of the neuronal differentiation abilities of bone marrow‑derived and adipose tissue‑derived mesenchymal stem cells

Y Zheng, C Huang, F Liu, H Lin… - Molecular …, 2017 - spandidos-publications.com
Bone marrow‑derived mesenchymal stem cells (BMSCs) and adipose tissue‑derived
mesenchymal stem cells (ADSCs) are able to differentiate into neuron‑like cells when …

Adoptive autophagy activation: a much-needed remedy against chemical induced neurotoxicity/developmental neurotoxicity

A Srivastava, V Kumar, A Pandey, S Jahan… - Molecular …, 2017 - Springer
The profound significance of autophagy as a cell survival mechanism under conditions of
metabolic stress is a well-proven fact. Nearly a decade-long research in this area has led …

Chlorpyrifos induces endoplasmic reticulum stress in JEG-3 cells

L Reyna, J Flores-Martín, ME Ridano… - Toxicology in Vitro, 2017 - Elsevier
Chlorpyrifos (CPF) is an organophosphorous pesticide widely used in agricultural, industrial,
and household applications. We have previously shown that JEG-3 cells are able to …

Neural-like cells from adipose-derived stem cells for cavernous nerve injury in rats

CC Ying, M Yang, Y Wang, YL Guo… - Neural Regeneration …, 2019 - journals.lww.com
Although the remaining nerve tissue can regenerate and partly restore erectile function
when the cavernous nerve is compressed/severed and function lost, the limited regenerative …

Study of lead-induced neurotoxicity in cholinergic cells differentiated from bone marrow-derived mesenchymal stem cells

E Jafarzadeh, M Soodi, T Tiraihi… - Toxicology and …, 2022 - journals.sagepub.com
The developing brain is susceptible to the neurotoxic effects of lead. Exposure to lead has
main effects on the cholinergic system and causes reduction of cholinergic neuron function …