Over the last decade, there has been a significant increase in average paternal age when
the first child is conceived, either due to increased life expectancy, widespread use of …

BACKGROUND Maternal factors, including increasing childbearing age and various life-
style factors, are associated with poorer short-and long-term outcomes for children, whereas …

Objective To synthesize the current knowledge on possible environmental risk factors for
Obsessive-Compulsive Disorder (OCD). Method We conducted a systematic review …

Background Despite substantial similarities and overlaps in the pathophysiology of
obsessive-compulsive disorders (OCD) and autism spectrum disorders, little is known about …

We review the hypotheses concerning the association between the paternal age at
childbearing and childhood psychiatric disorders (autism spectrum‐and attention …

Importance Despite a remarkable co-occurrence of obsessive-compulsive disorder (OCD)
and schizophrenia, little is known about the clinical and etiological relationship of these 2 …

Purpose Fertility at advanced age has become increasingly common, but the aging of
parents may adversely affect the maturation of gametes and the development of embryos …

There is robust evidence from epidemiological studies that the offspring of older fathers have
an increased risk of neurodevelopmental disorders, such as schizophrenia and autism. The …

A large number of studies have examined the association between advanced paternal age
(APA) and risk of schizophrenia in offspring. Here we present an overview of …

Paternal age at conception has been increasing. In this review, we first present the results
from the major mammalian animal models used to establish that increasing paternal age …