Unlocking the Friedel-Crafts arylation of primary aliphatic alcohols and epoxides driven by hexafluoroisopropanol
S Zhang, M Vayer, F Noel, VD Vuković, A Golushko… - Chem, 2021 - cell.com
Alcohols and epoxides are arguably ideal electrophiles for the Friedel-Crafts alkylation,
since they are widely available, require no pre-activation, and produce no stoichiometric …
since they are widely available, require no pre-activation, and produce no stoichiometric …
Synthesis of a Bicyclic Azetidine with In Vivo Antimalarial Activity Enabled by Stereospecific, Directed C(sp3)–H Arylation
The development of new antimalarial therapeutics is necessary to address the increasing
resistance to current drugs. Bicyclic azetidines targeting Plasmodium falciparum …
resistance to current drugs. Bicyclic azetidines targeting Plasmodium falciparum …
Thiazole analogues of the marine alkaloid nortopsentin as inhibitors of bacterial biofilm formation
A Carbone, S Cascioferro, B Parrino, D Carbone… - Molecules, 2020 - mdpi.com
Anti-virulence strategy is currently considered a promising approach to overcome the global
threat of the antibiotic resistance. Among different bacterial virulence factors, the biofilm …
threat of the antibiotic resistance. Among different bacterial virulence factors, the biofilm …
Intramolecular Fischer indole synthesis for the direct synthesis of 3, 4-fused tricyclic indole and application to the total synthesis of (−)-aurantioclavine
Aryl hydrazides with a ketone or aldehyde containing side chains linked to the meta-position
of the aromatic ring undergo acid-promoted intramolecular Fischer indole synthesis to …
of the aromatic ring undergo acid-promoted intramolecular Fischer indole synthesis to …
Nickel-catalyzed asymmetric hydrogenation of cyclic sulfamidate imines: Efficient synthesis of chiral cyclic sulfamidates
Y Liu, Z Yi, X Tan, XQ Dong, X Zhang - Iscience, 2019 - cell.com
Chiral cyclic sulfamidates are useful building blocks to construct compounds, such as chiral
amines, with important applications. Often these compounds can only be generated through …
amines, with important applications. Often these compounds can only be generated through …
Asymmetric azidohydroxylation of styrene derivatives mediated by a biomimetic styrene monooxygenase enzymatic cascade
L Martínez-Montero, D Tischler, P Süss… - Catalysis Science & …, 2021 - pubs.rsc.org
Enantioenriched azido alcohols are precursors for valuable chiral aziridines and 1, 2-amino
alcohols, however their chiral substituted analogues are difficult to access. We established a …
alcohols, however their chiral substituted analogues are difficult to access. We established a …
One Pot Asymmetric Synthesis of (R)‐Phenylglycinol from Racemic Styrene Oxide via Cascade Biocatalysis
ZB Sun, ZJ Zhang, FL Li, Y Nie, HL Yu, JH Xu - ChemCatChem, 2019 - Wiley Online Library
Abstract (R)‐Phenylglycinol is an important chiral building block for pharmaceutical and fine
chemical industry, and its efficient synthesis from cheap and commercially available starting …
chemical industry, and its efficient synthesis from cheap and commercially available starting …
Regiodivergent and stereoselective hydroxyazidation of alkenes by biocatalytic cascades
JF Wu, NW Wan, YN Li, QP Wang, BD Cui, WY Han… - Iscience, 2021 - cell.com
Asymmetric functionalization of alkenes allows the direct synthesis of a wide range of chiral
compounds. Vicinal hydroxyazidation of alkenes provides a desirable path to 1, 2 …
compounds. Vicinal hydroxyazidation of alkenes provides a desirable path to 1, 2 …
Enantioselective synthesis of γ-Phenyl-γ-amino vinyl phosphonates and sulfones and their application to the synthesis of novel highly potent antimalarials
EK Aratikatla, M Kalamuddin, P Malhotra… - ACS …, 2020 - ACS Publications
Racemic and enantioselective syntheses of γ-phenyl-γ-amino vinyl phosphonates and
sulfones have been achieved using Horner–Wadsworth–Emmons olefination of trityl …
sulfones have been achieved using Horner–Wadsworth–Emmons olefination of trityl …
[Fe3O4@SiO2@(CH2)3im]C6F5O as a New Hydrophilic and Task‐Specific Nanomagnetic Catalyst: Application for Synthesis of β‐Azido Alcohols and …
J Afsar, MA Zolfigol, A Khazaei - ChemistrySelect, 2018 - Wiley Online Library
Abstract [Fe3O4@ SiO2@(CH2) 3im] C6F5O was designed, synthesized and characterized
by various techniques such as Fourier transform spectroscopy infrared (FT‐IR), X‐ray …
by various techniques such as Fourier transform spectroscopy infrared (FT‐IR), X‐ray …