Thiram exposure in environment: A critical review on cytotoxicity

K Liu, Y Li, M Iqbal, Z Tang, H Zhang - Chemosphere, 2022 - Elsevier
Thiram is used in large quantities in agriculture and may contaminate the environment by
improper handling or storage in chemical plants and warehouses. A review of the literature …

Cellular, molecular and genetical overview of avian tibial dyschondroplasia

AR Jahejo, WX Tian - Research in Veterinary Science, 2021 - Elsevier
Tibial dyschondroplasia (TD) is an intractable avian bone disease that causes severe
poultry economic losses. The pathogenicity of TD is unknown. Therefore, TD disease has …

Molecular mechanism of thiram-induced abnormal chondrocyte proliferation via lncRNA MSTRG. 74.1-BNIP3 axis

X Wu, Y Liu, Y Li, Z Tang, A Li, H Zhang - Pesticide Biochemistry and …, 2024 - Elsevier
Thiram, a widely used organic pesticide in agriculture, exhibits both bactericidal and
insecticidal effects. However, prolonged exposure to thiram has been linked to bone …

[HTML][HTML] Thiram exposure induces tibial dyschondroplasia in broilers via the regulation effect of circ_003084/miR-130c-5p/BMPR1A crosstalk on chondrocyte …

H Xu, Y Jiang, Y Lu, Z Hu, R Du, Y Zhou, Y Liu… - Journal of Hazardous …, 2024 - Elsevier
Thiram, an agricultural insecticide, has been demonstrated to induce tibial dyschondroplasia
(TD) in avian species. Circular RNA (circRNAs), a novel class of functional biological …

[PDF][PDF] Tetramethylpyrazine mitigates toxicity and liver oxidative stress in tibial dyschondroplasia chickens.

K Mehmood, ZH Zhang Hui, MK Iqbal… - 2018 - pvj.com.pk
Avian tibial dyschondroplasia disease is common in fast growing chickens round the world
in which growth plate/cartilage accumulates in metaphyseal region of tibial bone, which is …

[HTML][HTML] Role and regulation of growth plate vascularization during coupling with osteogenesis in tibial dyschondroplasia of chickens

S Huang, L Zhang, J Zhang, MU Rehman, X Tong… - Scientific reports, 2018 - nature.com
Tibial dyschondroplasia (TD) is the most-prevalent leg disorder in fast-growing chickens; it is
intractable and characterized by abnormal endochondral bone formation of proximal tibial …

[HTML][HTML] Treatment of tibial dyschondroplasia with traditional Chinese medicines:“Lesson and future directions”

H Zhang, Y Wang, K Mehmood, YF Chang, Z Tang, Y Li - Poultry science, 2020 - Elsevier
Tibial dyschondroplasia (TD) is a metabolic tibiotarsal bone disease in rapidly growing birds
throughout the world, which is characterized by gait disorders, reduced growth, and in an …

Hsp90 inhibitor celastrol reinstates growth plate angiogenesis in thiram-induced tibial dyschondroplasia

F Nabi, M Shahzad, J Liu, K Li, Z Han, D Zhang… - Avian …, 2016 - Taylor & Francis
Tibial dyschondroplasia (TD) is an important long bone defect of broiler chickens that
disturbs the proximal growth plate and is characterized by non-vascularized cartilage, a …

[HTML][HTML] Effect of tetramethylpyrazine on tibial dyschondroplasia incidence, tibial angiogenesis, performance and characteristics via HIF-1α/VEGF signaling pathway in …

K Mehmood, H Zhang, K Li, L Wang, MU Rehman… - Scientific reports, 2018 - nature.com
Tibial dyschodroplasia (TD) is a most common pathological condition in many avian species
that is characterized by failure of growth plate (GP) modeling that leads to the persistence of …

[HTML][HTML] Icariin ameliorate thiram-induced tibial dyschondroplasia via regulation of WNT4 and VEGF expression in broiler chickens

H Zhang, K Mehmood, K Li, MU Rehman… - Frontiers in …, 2018 - frontiersin.org
Tibial dyschondroplasia (TD) is main bone problem in fast growing poultry birds that effect
proximal growth plate (GP) of tibia bone. TD is broadly defined as non-vascularized and non …