The advantages of high-precision dosing, manufacturing efficiency, and patient compliance
make tablets the most popular dosage forms. Compaction, an essential manufacturing step …

This review provides an insight into mechanical properties that are critical to understanding
powder processing for tableting. Various parameters that reflect these basic fundamental …

Presenting authoritative and engaging articles on all aspects of drug development, dosage,
manufacturing, and regulation, this Third Edition enables the pharmaceutical specialist and …

Great differences between published Heckel parameters, obtained from 'at pressure'data or
the 'in-die'method, are outlined. The general validity of the concept of yield pressures …

The ultimate goal of drug product development is to design a system that maximizes the
therapeutic potential of the drug substance and facilitates its access to patients …

The physical characteristics of raw materials determine powder compression and
compaction performance as relevant in pharmaceutical processes. For instance, the …

The purpose of this study is to investigate and to quantify the compactibility of
pharmaceutical powders by a simple linear relationship between the diametral compressive …

Poly (ethylene oxide) polymers (PEO) appear to have great potential for controlled release
applications. These polymers are hydrophilic with good water solubility, low toxicity, and …

In this review article, the techniques that have been utilized to assess the compactional
behaviour of pharmaceutical materials were presented, and the advantages, limitations and …

This study investigated deformation mechanisms of some commonly used pharmaceutical
fillers, such as microcrystalline cellulose, lactose, dicalcium phosphate, isomalt and …