Therapeutic advances for glioblastoma have been minimal over the past 2 decades. In light
of the multitude of recent phase III trials that have failed to meet their primary endpoints …

Glioblastoma (GBM) is highly invasive and the deadliest brain tumor in adults. It is
characterized by inter-tumor and intra-tumor heterogeneity, short patient survival, and lack of …

Background In the field of glioma, transcriptome subtypes have been considered as an
important diagnostic and prognostic biomarker that may help improve the treatment efficacy …

Simple Summary Glioblastoma is one of the most treatment-refractory human malignancies,
and despite techniques that have allowed scientists and clinicians to better understand the …

Background The biologic meaning of prognostic radiomics phenotypes remains poorly
understood, hampered in part by lack of multicenter reproducible evidence. Purpose To …

Glioblastoma (GBM) is the most common and aggressive malignant primary brain tumor in
adults. Its aggressive nature is attributed partly to its deeply invasive margins, its molecular …

Malignant brain tumors consist of malignancies originated primarily within the brain and the
metastatic lesions disseminated from other organs. In spite of intensive studies, malignant …

Background Chloride intracellular channel-1 (CLIC1) activity controls glioblastoma
proliferation. Metformin exerts antitumor effects in glioblastoma stem cells (GSCs) inhibiting …

Glioblastoma multiforme (GBM) is a devastating brain tumour without effective treatment.
Recent studies have shown that autophagy is a promising therapeutic strategy for GBM …

The permeability of glioblastoma, as well as its escaping the immune system, makes them
one of the most deadly human malignancies. By avoiding programmed cell death …