Treat-to-target in systemic lupus erythematosus: advancing towards its implementation

AR Parra Sánchez, AE Voskuyl… - Nature reviews …, 2022 - nature.com
The treat-to-target (T2T) concept has improved outcomes for patients with diabetes,
hypertension and rheumatoid arthritis. This therapeutic strategy involves choosing a well …

Relationship between disease activity, organ damage and health-related quality of life in patients with systemic lupus erythematosus: A systemic review and meta …

Y Shi, M Li, L Liu, Z Wang, Y Wang, J Zhao, Q Wang… - Autoimmunity …, 2021 - Elsevier
Objectives Systemic lupus erythematosus (SLE) is a common systemic autoimmune disease
that may lead to considerable physical, psychological, and socioeconomical burden. In …

2021 DORIS definition of remission in SLE: final recommendations from an international task force

RF van Vollenhoven, G Bertsias, A Doria… - Lupus science & …, 2021 - lupus.bmj.com
Objective To achieve consensus on a definition of remission in SLE (DORIS). Background
Remission is the stated goal for both patient and caregiver, but consensus on a definition of …

Treatment targets in SLE: remission and low disease activity state

V Golder, MWP Tsang-A-Sjoe - Rheumatology, 2020 - academic.oup.com
Treat-to-target strategies have changed the approach to management of many chronic
conditions, with improvements in patient outcomes. The key to success of treat to target is …

Achieving remission or low disease activity is associated with better outcomes in patients with systemic lupus erythematosus: a systematic literature review

MF Ugarte-Gil, C Mendoza-Pinto… - Lupus science & …, 2021 - lupus.bmj.com
Background Remission and low disease activity (LDA) have been proposed as the treatment
goals for patients with systemic lupus erythematosus (SLE). Several definitions for each …

Impact of remission and low disease activity on health-related quality of life in patients with systemic lupus erythematosus

S Emamikia, S Oon, A Gomez, J Lindblom… - …, 2022 - academic.oup.com
Objectives To investigate the impact of remission and lupus low disease activity state
(LLDAS) on health-related quality of life (HRQoL) in systemic lupus erythematosus. Methods …

[HTML][HTML] Adverse health-related quality of life outcome despite adequate clinical response to treatment in systemic lupus erythematosus

A Gomez, V Qiu, A Cederlund, A Borg… - Frontiers in …, 2021 - frontiersin.org
Objective: To determine the prevalence of adverse health-related quality of life (HRQoL)
outcomes in patients with SLE who achieved an adequate clinical response after a 52-week …

One year in review 2020: systemic lupus erythematosus

V Signorini, E Elefante, D Zucchi, F Trentin… - Clinical and …, 2020 - sfera.unife.it
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a relapsing-
remitting course that can affect various organs or systems, leading to a broad spectrum of …

[HTML][HTML] Articular involvement, steroid treatment and fibromyalgia are the main determinants of patient-physician discordance in systemic lupus erythematosus

E Elefante, C Tani, C Stagnaro, V Signorini… - Arthritis Research & …, 2020 - Springer
Background Remission or the lowest possible disease activity is the main target in the
management of systemic lupus erythematosus (SLE). Anyway, conflicting data are present in …

The patient's perspective: are quality of life and disease burden a possible treatment target in systemic lupus erythematosus?

A Kernder, E Elefante, G Chehab, C Tani… - …, 2020 - academic.oup.com
A few decades ago, the therapy goal of patients with systemic lupus erythematosus (SLE)
was survival and the prevention of organ failure. Today, clinical remission and low disease …