Survivin: a unique target for tumor therapy
Survivin is the smallest member of the Inhibitor of apoptosis (IAP) family of proteins, involved
in inhibition of apoptosis and regulation of cell cycle. These functional attributes make …
in inhibition of apoptosis and regulation of cell cycle. These functional attributes make …
The survivin molecule as a double‐edged sword in cellular physiologic and pathologic conditions and its role as a potential biomarker and therapeutic target in cancer
A Rafatmanesh, M Behjati, N Mobasseri… - Journal of Cellular …, 2020 - Wiley Online Library
Survivin is a member of the family of apoptosis inhibitory proteins with increased expression
level in most cancerous tissues. Evidence shows that survivin plays regulatory roles in …
level in most cancerous tissues. Evidence shows that survivin plays regulatory roles in …
BIRC5 Gene Polymorphisms Are Associated with a Higher Stage of Local and Regional Disease in Oral and Oropharyngeal Squamous Cell Carcinomas
Oral squamous cell carcinoma (OSCC) and oropharyngeal squamous cell carcinoma
(OPSCC) are the most common types of cancers in the head and neck region (HNSCC) …
(OPSCC) are the most common types of cancers in the head and neck region (HNSCC) …
Clinico-pathologic relevance of Survivin splice variant expression in cancer
R de Necochea-Campion, CS Chen, S Mirshahidi… - Cancer letters, 2013 - Elsevier
Survivin is a member of the inhibitor of apoptosis (IAP) family and has multifunctional
properties that include aspects of proliferation, invasion and cell survival control. Survivin is …
properties that include aspects of proliferation, invasion and cell survival control. Survivin is …
Survivin in breast cancer: a review
MA Martínez-Sifuentes… - Genetic Testing and …, 2022 - liebertpub.com
Breast cancer is the most frequently diagnosed cancer in women and ranks second among
causes for cancer-related death in women. Gene technology has led to the recognition that …
causes for cancer-related death in women. Gene technology has led to the recognition that …
Survivin expression impacts prognostically on NSCLC but not SCLC
A Rosato, C Menin, D Boldrin, S Dalla Santa, L Bonaldi… - Lung Cancer, 2013 - Elsevier
Survivin is expressed in lung cancer and in most cancer tissues and has a significant impact
on prognosis. This work aimed to comparatively assess survivin expression and significance …
on prognosis. This work aimed to comparatively assess survivin expression and significance …
microRNA involvement in the regulation of survivin in peripheral blood mononuclear cells from rheumatoid arthritis patients
H Ebrahimiyan, N Rezaei, M Vojdanian… - International Journal …, 2019 - Wiley Online Library
Aim Impaired regulation of immune tolerance results in autoimmune diseases, such as
rheumatoid arthritis (RA). Survivin is an anti‐apoptotic protein and can induce cellular …
rheumatoid arthritis (RA). Survivin is an anti‐apoptotic protein and can induce cellular …
Polymorphisms in Survivin (BIRC5 Gene) Are Associated with Age of Onset in Breast Cancer Patients
I Sušac, P Ozretić, M Gregorić… - Journal of …, 2019 - Wiley Online Library
Survivin, encoded by BIRC5 gene (baculoviral IAP repeat containing 5), belongs to the
family of inhibitors of apoptosis proteins (IAPs). In mammalian cells it participates in the …
family of inhibitors of apoptosis proteins (IAPs). In mammalian cells it participates in the …
High expression of survivin and its splice variants survivin ΔEx3 and survivin 2 B in oral cancers
Objectives We have previously reported inactivation of p53 in 46% of Indian patients with
oral cancer. Survivin, a p53 target gene and an inhibitor of apoptosis protein (IAP), is …
oral cancer. Survivin, a p53 target gene and an inhibitor of apoptosis protein (IAP), is …
Survivin gene promoter polymorphism‐31G/C as a risk factor for keratocystic odontogenic tumor development
M Andric, N Nikolic, M Boskovic… - European journal of …, 2012 - Wiley Online Library
Andric M, Nikolic N, Boskovic M, Milicic B, Skodric S, Basta Jovanovic G, Milasin J. Survivin
gene promoter polymorphism‐31G/C as a risk factor for keratocystic odontogenic tumor …
gene promoter polymorphism‐31G/C as a risk factor for keratocystic odontogenic tumor …