Senescent cells accumulate throughout the body with advanced age, diseases and chronic
conditions. They negatively impact health and function of multiple systems, including the …

Cellular senescence, a process in which a cell exits the cell cycle in response to stressors, is
one of the hallmarks of aging. Senescence and the senescence-associated secretory …

The ketogenic diet (KD) has been shown to be effective in treating various brain pathologies.
In this study, we conducted detailed transcriptomic and metabolomic profiling of rat brains …

Traumatic brain injury (TBI) remains a leading cause of death and disability that places a
great physical, social, and financial burden on individuals and the health system. In this …

Objective Genome‐wide association studies implicate metabo‐psychiatric origins for
anorexia nervosa (AN). There are two case reports totaling six adult females who …

Background: Exercise and dietary interventions are essential for maintaining weight and
reducing fat accumulation. With the growing popularity of various dietary strategies …

It has been recognized for over a century that feeding animals less food than they would
normally eat increases lifespan and leads to broad-spectrum improvements in age-related …

Epilepsy is a chronic neurological disorder caused by abnormal discharges of neurons in
the brain, which seriously affects the quality of life of patients. Although there are various …

Metabolic dysfunction-associated steatotic liver disease (MASLD) is a metabolic disorder
marked by excessive accumulation of lipids within the liver. If untreated, this condition can …

The ketogenic diet (KD) is a high-fat, low-carbohydrate diet that results in the elevation of
serum ketone bodies, known as ketosis. This metabolic consequence has been suggested …