Physiology of astroglia

A Verkhratsky, M Nedergaard - Physiological reviews, 2018 - journals.physiology.org
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

Astrocytic neurotransmitter receptors in situ and in vivo

JT PORTER, KEN D MCCARTHY - Progress in neurobiology, 1997 - Elsevier
In the brain, astrocytes are associated intimately with neurons and surround synapses. Due
to their close proximity to synaptic clefts, astrocytes are in a prime location for receiving …

Control of gap-junctional communication in astrocytic networks

C Giaume, KD McCarthy - Trends in neurosciences, 1996 - cell.com
Astrocytes, which constitute the most abundant cell type in mammalian brain, are extensively
coupled to one another through gap junctions composed mainly of connexin43. In regions …

Receptors on astrocytes—what possible functions?

HK Kimelberg - Neurochemistry international, 1995 - Elsevier
Receptors for transmitters, as varied as those expressed by neurons, have been described
on primary astrocyte cultures prepared from new-born rats and mice. A variety of functional …

Molecular cloning of a somatostatin-28 receptor and comparison of its expression pattern with that of a somatostatin-14 receptor in rat brain.

W Meyerhof, I Wulfsen, C Schönrock… - Proceedings of the …, 1992 - National Acad Sciences
The tetradecapeptide somatotropin-release inhibiting factor somatostatin-14 regulates the
release of peptide hormones and also functions as neurotransmitter. The octacosapeptide …

Purification of the main somatostatin‐degrading proteases from rat and pig brains, their action on other neuropeptides, and their identification as endopeptidases …

P Dahms, R Mentlein - European Journal of Biochemistry, 1992 - Wiley Online Library
The main somatostatin‐degrading proteases were purified from rat and pig brain
homogenates and characterized as thiol‐and metal‐dependent endoproteases. Two types …

Endopeptidases 24.16 and 24.15 are responsible for the degradation of somatostatin, neurotensin, and other neuropeptides by cultivated rat cortical astrocytes

R Mentlein, P Dahms - Journal of neurochemistry, 1994 - Wiley Online Library
Several neuropeptides, including neurotensin, somatostatin, bradykinin, angiotensin II,
substance P, and luteinizing hormone‐releasing hormone but not vasopressin and oxytocin …

High sensitivity of the in vivo detection of somatostatin receptors by111Indium (DTPA-octreotide)-scintigraphy in meningioma patients

G Hildebrandt, K Scheidhauer, C Luyken, H Schicha… - Acta …, 1994 - Springer
The recent availability of isotope-labelled somatostatin analogues has allowed one to detect
somatostatin receptors in normal tissue as well as in endocrine or non-endocrine cranial …

Peptide receptors in astroglia: focus on angiotensin II and atrial natriuretic peptide

C Sumners, W Tang, W Paulding, MK Raizada - Glia, 1994 - Wiley Online Library
Astroglial cells derived from the mammalian central nervous system contain a wide variety of
peptide receptors, including specific sites for angiotensin II (AII) and atrial natriuretic peptide …

Immunoelectronmicroscopic analysis of the ligand-induced internalization of the somatostatin receptor subtype 2 in cultured human glioma cells

B Krisch, J Feindt, R Mentlein - Journal of Histochemistry & …, 1998 - journals.sagepub.com
We analyzed the internalization of the receptor subtype 2 (sst2) for the neuropeptide
somatostatin in glioma cells at the ultrastructural level using an antibody against an …