[HTML][HTML] Commonalities of optic nerve injury and glaucoma-induced neurodegeneration: Insights from transcriptome-wide studies
Glaucoma is a collection of diseases that lead to an irreversible vision loss due to damage of
retinal ganglion cells (RGCs). Although the underlying events leading to RGC death are not …
retinal ganglion cells (RGCs). Although the underlying events leading to RGC death are not …
Use of gene therapy for optic nerve protection: Current concepts
K Xu, L Yu, Z Wang, P Lin, N Zhang, Y Xing… - Frontiers in …, 2023 - frontiersin.org
Gene therapy has become an essential treatment for optic nerve injury (ONI) in recent years,
and great strides have been made using animal models. ONI, which is characterized by the …
and great strides have been made using animal models. ONI, which is characterized by the …
Blood pressure and glaucomatous progression in a large clinical population
Purpose To investigate the effect of systemic arterial blood pressure (BP) on rates of
progressive structural damage over time in glaucoma. Design Retrospective cohort study …
progressive structural damage over time in glaucoma. Design Retrospective cohort study …
Impact of smoking on visual field progression in a long-term clinical follow-up
Purpose To investigate the effect of smoking on rates of progressive visual field (VF)
damage over time in glaucoma. Design Retrospective cohort study. Participants Five …
damage over time in glaucoma. Design Retrospective cohort study. Participants Five …
The effect of age on increasing susceptibility to retinal nerve fiber layer loss in glaucoma
Purpose: To determine whether aging modifies the effect of intraocular pressure (IOP) on
progressive glaucomatous retinal nerve fiber layer (RNFL) thinning over time. Methods: This …
progressive glaucomatous retinal nerve fiber layer (RNFL) thinning over time. Methods: This …
GRAPE: A multi-modal dataset of longitudinal follow-up visual field and fundus images for glaucoma management
As one of the leading causes of irreversible blindness worldwide, glaucoma is characterized
by structural damage and functional loss. Glaucoma patients often have a long follow-up …
by structural damage and functional loss. Glaucoma patients often have a long follow-up …
Rapid initial OCT RNFL thinning is predictive of faster visual field loss during extended follow-up in glaucoma
SS Swaminathan, AA Jammal, SI Berchuck… - American journal of …, 2021 - Elsevier
Purpose To investigate the relationship between the rate of retinal nerve fiber layer (RNFL)
loss during initial follow-up and the magnitude of associated visual field loss during an …
loss during initial follow-up and the magnitude of associated visual field loss during an …
Novel Carbonic Anhydrase Inhibitors with Dual-Tail Core Sulfonamide Show Potent and Lasting Effects for Glaucoma Therapy
A Angeli, I Chelli, L Lucarini… - Journal of Medicinal …, 2024 - ACS Publications
Glaucoma, a leading cause of irreversible vision loss worldwide, is characterized by
elevated intraocular pressure (IOP), a well-established risk factor across all its forms. We …
elevated intraocular pressure (IOP), a well-established risk factor across all its forms. We …
Cost-effectiveness analysis of minimally invasive trabecular meshwork stents with phacoemulsification
Purpose To investigate the costs and effects of implanting trabecular meshwork bypass
stents during cataract surgery from a societal perspective in the United States. Design Cost …
stents during cataract surgery from a societal perspective in the United States. Design Cost …
A deep-learning system predicts glaucoma incidence and progression using retinal photographs
Background Deep learning has been widely used for glaucoma diagnosis. However, there is
no clinically validated algorithm for glaucoma incidence and progression prediction. This …
no clinically validated algorithm for glaucoma incidence and progression prediction. This …