Several of the most commonly used methods for in vitro determination of antioxidant
capacity are reviewed in the present paper. The chemical principles of methods based either …

This review is aimed at updating the current advance of metal complexes bearing
acylpyrazolonate ligands. Novel synthetic procedures for acylpyrazolones are reported …

Neutrophils play an important role in innate immunity by defending the host organism
against invading microorganisms. Antimicrobial activity of neutrophils is mediated by release …

Rosmarinic acid is a polyphenolic compound and main constituent of R osmarinus officinalis
and has been shown to possess antioxidant and anti‐inflammatory properties. We aimed to …

4-Aminoantipyrine (4-amino-1, 5-dimethyl-2-phenylpyrazole-3-one) and its analogues have
been found to be compounds of interest for their anti-inflammatory, analgesic, antiviral …

The formation of neutrophil extracellular traps (NETs) depends on the generation of reactive
oxygen species (ROS). Previous studies revealed that both NADPH oxidase and …

The health benefits of bio-active phenolic compounds have been largely investigated in vitro
at concentrations which exceed those reachable in vivo. We investigated and compared the …

A visible-light-mediated an effective organocatalytic synthesis of bioactive spiropyrazolones
has been described here. This photoredox synthetic approach includes metal free …

The first organocatalytic Michael–cyclization cascade reaction between isothiocyanato
oxindoles and unsaturated pyrazolones has been developed. The multicyclic spiro …

Background and Purpose: Dipyrone is a potent analgesic drug that has been demonstrated
to inhibit cyclooxygenase (COX). In contrast to classical COX‐inhibitors, such as aspirin‐like …