From actin waves to mechanism and back: how theory aids biological understanding
Actin dynamics in cell motility, division, and phagocytosis is regulated by complex factors
with multiple feedback loops, often leading to emergent dynamic patterns in the form of …
with multiple feedback loops, often leading to emergent dynamic patterns in the form of …
The excitable nature of polymerizing actin and the Belousov-Zhabotinsky reaction
The intricate regulatory processes behind actin polymerization play a crucial role in cellular
biology, including essential mechanisms such as cell migration or cell division. However, the …
biology, including essential mechanisms such as cell migration or cell division. However, the …
Nanotopography modulates intracellular excitable systems through cytoskeleton actuation
Cellular sensing of most environmental cues involves receptors that affect a signal-
transduction excitable network (STEN), which is coupled to a cytoskeletal excitable network …
transduction excitable network (STEN), which is coupled to a cytoskeletal excitable network …
Excitable systems: A new perspective on the cellular impact of elongate mineral particles
S Gu, A Bull, JK Perry, A Huang, MJ Hourwitz… - Environmental …, 2023 - Elsevier
We investigate how the geometry of elongate mineral particles (EMPs) in contact with cells
influences esotaxis, a recently discovered mechanism of texture sensing. Esotaxis is based …
influences esotaxis, a recently discovered mechanism of texture sensing. Esotaxis is based …
Decoding natural astrocyte rhythms: dynamic actin waves result from environmental sensing by primary rodent astrocytes
Astrocytes are key regulators of brain homeostasis, equilibrating ion, water, and
neurotransmitter concentrations and maintaining essential conditions for proper cognitive …
neurotransmitter concentrations and maintaining essential conditions for proper cognitive …
Machine learning from limited data: Predicting biological dynamics under a time-varying external input
H Kang, K Srinivasan, W Losert - arXiv preprint arXiv:2408.07998, 2024 - arxiv.org
Reservoir computing (RC) is known as a powerful machine learning approach for learning
complex dynamics from limited data. Here, we use RC to predict highly stochastic dynamics …
complex dynamics from limited data. Here, we use RC to predict highly stochastic dynamics …
Electrotaxis disrupts patterns of cell-cell interactions of human corneal epithelial cells in vitro
RM Crossley, SF Martina-Perez - bioRxiv, 2024 - biorxiv.org
Electrotaxis, the process by which eukaryotic cells establish a polarity and move
directionally along an electric field, is a well-studied mechanism to steer the migration of …
directionally along an electric field, is a well-studied mechanism to steer the migration of …
Coupled Biomechanical and Ionic Excitability in Developing Neural Cell Networks
Waves and oscillations play a key role in the flow and processing of information in the brain.
Recent work has demonstrated that in addition to electrical activity, biomechanical signaling …
Recent work has demonstrated that in addition to electrical activity, biomechanical signaling …
Data driven approach towards quantifying dynamics in biological systems
S Saha - 2023 - search.proquest.com
In this thesis, we develop data driven formalism for analysing features that govern dynamics
in biological systems. We first consider the social amoeba Dictyostelium discoideum as a …
in biological systems. We first consider the social amoeba Dictyostelium discoideum as a …
Collective Dynamics of Astrocyte and Cytoskeletal Systems
NJ Mennona - 2024 - search.proquest.com
Advances in imaging and biological sample preparations now allow researchers to study
collective behavior in cellular networks with unprecedented detail. Imaging the electrical …
collective behavior in cellular networks with unprecedented detail. Imaging the electrical …