Circulation of cerebrospinal fluid and interstitial fluid around the central nervous system and
through the brain transports not only those water-like fluids but also any solutes they carry …

The cognitive neuroscience of brain diseases faces challenges in understanding the
complex relationship between brain structure and function, the heterogeneity of brain …

Perivascular spaces are important highways for fluid and solute transport in the brain
enabling efficient waste clearance during sleep. However, the underlying mechanisms …

Objective Emerging pathological evidence suggests that there is an association between
glymphatic dysfunction and the progression of Parkinson's disease (PD). However, the …

Quantifying the flow of cerebrospinal fluid (CSF) is crucial for understanding brain waste
clearance and nutrient delivery, as well as edema in pathological conditions such as stroke …

Slow paced breathing via heart rate variability (HRV) biofeedback stimulates vagus-nerve
pathways that counter noradrenergic stress and arousal pathways that can influence …

Background Diffusion imaging holds great potential for the non‐invasive assessment of the
glymphatic system in humans. One technique, diffusion tensor imaging along the …

Meningeal lymphatic vessels (MLVs) promote tissue clearance and immune surveillance in
the central nervous system (CNS). Vascular endothelial growth factor-C (VEGF-C) regulates …

The flow of cerebrospinal fluid (CSF) along perivascular spaces (PVSs) is an important part
of the brain's system for clearing metabolic waste. Experiments reveal that arterial motions …

The brain extracellular space (ECS) is a vast interstitial reticulum of extreme morphological
complexity, composed of narrow gaps separated by local expansions, enabling …