[HTML][HTML] Antioxidant properties of flavonoid metal complexes and their potential inclusion in the development of novel strategies for the treatment against …

E Rodríguez-Arce, M Saldías - Biomedicine & Pharmacotherapy, 2021 - Elsevier
The increased oxidative stress in the acceleration of the aging process and development of
the neuronal disorder are the common feature detected in neurodegenerative illness, such …

In vivo imaging with genetically encoded redox biosensors

AI Kostyuk, AS Panova, AD Kokova, DA Kotova… - International journal of …, 2020 - mdpi.com
Redox reactions are of high fundamental and practical interest since they are involved in
both normal physiology and the pathogenesis of various diseases. However, this area of …

Metallomics and other omics approaches in antiparasitic metal-based drug research

G Scalese, K Kostenkova, DC Crans… - Current opinion in …, 2022 - Elsevier
Potential use of metal complexes in medicine is an area of bioinorganic chemistry that has
gained much interest. High-throughput omics approaches can provide in-depth insights into …

Design of prospective antiparasitic metal-based compounds including selected organometallic cores

D Gambino, L Otero - Inorganica Chimica Acta, 2018 - Elsevier
A group of seventeen communicable and poverty-related diseases are considered
neglected by the World Health Organization due to the restricted development of diagnostic …

Facing diseases caused by trypanosomatid parasites: rational design of Pd and Pt complexes with bioactive ligands

D Gambino, L Otero - Frontiers in Chemistry, 2022 - frontiersin.org
Human African Trypanosomiasis (HAT), Chagas disease or American Trypanosomiasis
(CD), and leishmaniases are protozoan infections produced by trypanosomatid parasites …

Heteroleptic Oxidovanadium(V) Complexes with Activity against Infective and Non-Infective Stages of Trypanosoma cruzi

G Scalese, I Machado, G Salinas, L Pérez-Díaz… - Molecules, 2021 - mdpi.com
Five heteroleptic compounds,[VVO (IN-2H)(LH)], where L are 8-hydroxyquinoline derivatives
and IN is a Schiff base ligand, were synthesized and characterized in both the solid and …

New multifunctional Ru (II) organometallic compounds show activity against Trypanosoma brucei and Leishmania infantum

F Rivas, C Del Mármol, G Scalese, L Pérez-Díaz… - Journal of Inorganic …, 2022 - Elsevier
Human African trypanosomiasis (sleeping sickness) and leishmaniasis are prevalent
zoonotic diseases caused by genomically related trypanosomatid protozoan parasites …

Metallodrugs for the treatment of trypanosomatid diseases: Recent advances and new insights

M Navarro, RMS Justo, GYS Delgado… - Current …, 2021 - benthamdirect.com
Trypanosomatid parasites are responsible for many Neglected Tropical Diseases (NTDs).
NTDs are a group of illnesses that prevail in low-income populations, such as in tropical and …

Heteroleptic pincer palladium (II) complex coated orthopedic implants impede the AbaI/AbaR quorum sensing system and biofilm development by Acinetobacter …

S Jothipandiyan, D Suresh, SV Sankaran… - Biofouling, 2022 - Taylor & Francis
Implant-associated infections mediated by Acinetobacter baumannii biofilms have become a
major concern in the healthcare sector. As biofilm formation by this important pathogen is …

Facing diseases caused by trypanosomatid parasites: rational design of multifunctional oxidovanadium (IV) complexes with bioactive ligands

G Scalese, I Machado, F Salazar, EL Coitiño… - Frontiers in Chemical …, 2024 - frontiersin.org
Searching for new prospective drugs against Chagas disease (American trypanosomiasis)
and Leishmaniasis, a series of five heteroleptic vanadium compounds,[VIVO (LH)(mpo)] …