Recent advances in the synthesis and CF functionalization of gem-difluoroalkenes

X Zhang, S Cao - Tetrahedron Letters, 2017 - Elsevier
The gem-difluoroalkenes and related compounds have gained much attention from the
organic synthetic community due to their widespread applications as versatile fluorinated …

CF bond activation under transition-metal-free conditions

HJ Ai, X Ma, Q Song, XF Wu - Science China Chemistry, 2021 - Springer
The unique properties of fluorine-containing organic compounds make fluorine substitution
attractive for the development of pharmaceuticals and various specialty materials, which …

Recent advancements in typical friedel–crafts alkylation reactions focused on targeting arene nucleophiles

S Singh, CK Hazra - Synthesis, 2024 - thieme-connect.com
This review delves into recent advances and significant breakthroughs in the field of the
catalytic Friedel–Crafts alkylation of targeted arenes or heteroarenes. Though a few earlier …

Multiple-fold C–F bond functionalization for the synthesis of (hetero) cyclic compounds: fluorine as a detachable chemical handle

D Ge, XQ Chu - Organic Chemistry Frontiers, 2022 - pubs.rsc.org
Although the demand for privileged (hetero) cyclic molecules continues to grow steadily in
organic synthesis, drug discovery, agrochemical chemistry, materials science, etc., the …

Cu-Catalyzed tertiary alkylation of α-(trifluoromethyl) styrenes with tertiary alkylmagnesium reagents

W Dai, Y Lin, Y Wan, S Cao - Organic Chemistry Frontiers, 2018 - pubs.rsc.org
Cu-Catalyzed tertiary alkylation of α-(trifluoromethyl)styrenes with tertiary alkylmagnesium
reagents - Organic Chemistry Frontiers (RSC Publishing) DOI:10.1039/C7QO00716G Royal …

Heteroannulation enabled by a bimetallic Rh (III)/Ag (I) relay catalysis: application in the total synthesis of aristolactam BII

WW Ji, E Lin, Q Li, H Wang - Chemical Communications, 2017 - pubs.rsc.org
A redox-neutral bimetallic Rh (III)/Ag (I) relay catalysis allowed the efficient construction of 3-
alkylidene isoindolinones and 3-alkylidene isobenzofuranones. The Rh (III) catalyst was …

Synthesis of extended polycyclic aromatic hydrocarbons by oxidative tandem spirocyclization and 1, 2-aryl migration

X Zhang, Z Xu, W Si, K Oniwa, M Bao… - Nature …, 2017 - nature.com
The extended polycyclic aromatic hydrocarbons (PAHs) have received significant
interdisciplinary attention due to their semiconducting applications in diverse organic …

The Rolling‐Up of Oligophenylenes to Nanographenes by a HF‐Zipping Approach

AK Steiner, KY Amsharov - Angewandte Chemie International …, 2017 - Wiley Online Library
Intramolecular aryl–aryl coupling is the key transformation in the rational synthesis of
nanographenes and nanoribbons. In this respect the C− F bond activation was shown to be …

Effect of Internal Substituents on the Properties of Dibenzo[g,p]chrysene

Y Takeo, J Hirano, N Fukui, H Shinokubo - Organic Letters, 2023 - ACS Publications
We investigated the chemical and physical properties of internally functionalized dibenzo [g,
p] chrysene (DBC) derivatives. These molecules exhibit chiral double-helicene-like …

New one-pot synthesis of N-fused isoquinoline derivatives by palladium-catalyzed C–H arylation: potent inhibitors of nucleotide pyrophosphatase-1 and-3

E Ausekle, SA Ejaz, SU Khan, P Ehlers… - Organic & …, 2016 - pubs.rsc.org
Various N-fused isoquinoline derivatives were synthesized using a new one-pot reaction of
1-bromo-2-(2, 2-difluorovinyl) benzenes with N–H group containing heterocycles followed …