The measurement of vascular function in isolated vessels has revealed important insights
into the structural, functional, and biomechanical features of the normal and diseased …

Perivascular adipose tissue (PVAT) is a specialized type of adipose tissue that surrounds
most mammalian blood vessels. PVAT is a metabolically active, endocrine organ capable of …

Perivascular adipose tissue (PVAT) is a special type of ectopic fat depot that adheres to most
vasculatures. PVAT has been shown to exert anticontractile effects on the blood vessels and …

Objective: The mechanisms involved in NOX5 activation in atherosclerotic processes are not
completely understood. The present study tested the hypothesis that …

Sustained hyperglycemia results in excess protein O-GlcNAcylation, leading to vascular
complications in diabetes. This study aims to investigate the role of O-GlcNAcylation in the …

Background Posttranslational protein modification with O‐linked N‐acetylglucosamine (O‐
Glc NA c) is linked to high glucose levels in type 2 diabetes mellitus (T2 DM) and may alter …

Sepsis is a systemic inflammatory response syndrome (SIRS) resulting from a severe
infection that is characterized by immune dysregulation, cardiovascular derangements, and …

Glycation and glycosylation are non-enzymatic and enzymatic reactions, respectively, of
glucose, glucose metabolites, and other reducing sugars with different substrates, such as …

Cardiovascular diseases (CVDs) are the leading cause of death globally. While the major
focus of pharmacological and non-pharmacological interventions has been on targeting …

Perivascular adipose tissue (PVAT) is the connective tissue surrounding most of the
systemic blood vessels. PVAT is now recognized as an important endocrine tissue that …