Long‐term adverse effects of paracetamol–a review

JC McCrae, EE Morrison, IM MacIntyre… - British journal of …, 2018 - Wiley Online Library
Paracetamol (acetaminophen) is the most commonly used drug in the world, with a long
record of use in acute and chronic pain. In recent years, the benefits of paracetamol use in …

Analysis and reporting of adverse events in randomised controlled trials: a review

R Phillips, L Hazell, O Sauzet, V Cornelius - BMJ open, 2019 - bmjopen.bmj.com
Objective To ascertain contemporary approaches to the collection, reporting and analysis of
adverse events (AEs) in randomised controlled trials (RCTs) with a primary efficacy …

[图书][B] Principles of biostatistics

M Pagano, K Gauvreau, H Mattie - 2022 - taylorfrancis.com
Principles of Biostatistics, Third Edition is a concepts-based introduction to statistical
procedures that prepares public health, medical, and life sciences students to conduct and …

Individualized therapy for persistent asthma in young children

AM Fitzpatrick, DJ Jackson, DT Mauger… - Journal of Allergy and …, 2016 - Elsevier
Background Phenotypic presentations in young children with asthma are varied and might
contribute to differential responses to asthma controller medications. Methods The …

Gut microbiota mediates diurnal variation of acetaminophen induced acute liver injury in mice

S Gong, T Lan, L Zeng, H Luo, X Yang, NA Li… - Journal of …, 2018 - Elsevier
Background & Aims Acetaminophen (APAP) induced hepatotoxicity is a leading cause of
acute liver failure worldwide. It is well established that the liver damage induced by …

Comparison of acetaminophen (paracetamol) with ibuprofen for treatment of fever or pain in children younger than 2 years: a systematic review and meta-analysis

E Tan, I Braithwaite, CJD McKinlay… - JAMA network …, 2020 - jamanetwork.com
Importance Acetaminophen (paracetamol) and ibuprofen are the most widely prescribed
and available over-the-counter medications for management of fever and pain in children …

Efficacy and safety of NSAIDs in infants: a comprehensive review of the literature of the past 20 years

VC Ziesenitz, T Welzel, M van Dyk, P Saur, M Gorenflo… - Pediatric Drugs, 2022 - Springer
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used in infants, children, and
adolescents worldwide; however, despite sufficient evidence of the beneficial effects of …

Exploring species-level infant gut bacterial biodiversity by meta-analysis and formulation of an optimized cultivation medium

G Alessandri, F Fontana, L Mancabelli… - npj Biofilms and …, 2022 - nature.com
In vitro gut cultivation models provide host-uncoupled, fast, and cost-efficient solutions to
investigate the effects of intrinsic and extrinsic factors impacting on both composition and …

[图书][B] Acetylsalicylic acid

K Schrör - 2016 - books.google.com
Written by a leading expert on Aspirin-related research, this is the most comprehensive
treatise on the pharmacological effects and clinical applications of one of the most …

Prevention of asthma: targets for intervention

MC Maciag, W Phipatanakul - Chest, 2020 - Elsevier
Approximately 300 million people worldwide are estimated to be affected by asthma, and the
number of patients affected is growing exponentially—with potential for an additional 100 …