[HTML][HTML] Interactions between NSAIDs, opioids and the gut microbiota-future perspectives in the management of inflammation and pain
The composition of intestinal microbiota is influenced by a number of factors, including
medications, which may have a substantial impact on host physiology. Nonsteroidal anti …
medications, which may have a substantial impact on host physiology. Nonsteroidal anti …
Therapeutic promises of medicinal plants in Bangladesh and their bioactive compounds against ulcers and inflammatory diseases
When functioning properly, the stomach is the center of both physical and mental
satisfaction. Gastrointestinal disorders, or malfunctioning of the stomach, due to infections …
satisfaction. Gastrointestinal disorders, or malfunctioning of the stomach, due to infections …
Diclofenac induced gastrointestinal and renal toxicity is alleviated by thymoquinone treatment
İÖ Aycan, Ö Elpek, B Akkaya, E Kıraç, H Tuzcu… - Food and Chemical …, 2018 - Elsevier
The aim of this study was to investigate whether thymoquinone (TQ) could alleviate
diclofenac (DCLF)-induced gastrointestinal and renal toxicity in rats. Diclofenac was …
diclofenac (DCLF)-induced gastrointestinal and renal toxicity in rats. Diclofenac was …
[HTML][HTML] A comprehensive time course and correlation analysis of indomethacin-induced inflammation, bile acid alterations and dysbiosis in the rat small intestine
B Lázár, SB László, B Hutka, AS Tóth… - Biochemical …, 2021 - Elsevier
It has been proposed that changes in microbiota due to nonsteroidal anti-inflammatory drugs
(NSAIDs) alter the composition of bile, and elevation of hydrophobic secondary bile acids …
(NSAIDs) alter the composition of bile, and elevation of hydrophobic secondary bile acids …
Glycomacropeptide ameliorates indomethacin-induced enteropathy in rats by modifying intestinal inflammation and oxidative stress
D Cervantes-García, AI Bahena-Delgado, M Jiménez… - Molecules, 2020 - mdpi.com
Nonsteroidal anti-inflammatory drug (NSAID)-induced enteropathy is considered a serious
and increasing clinical problem without available treatment. Glycomacropeptide (GMP) is a …
and increasing clinical problem without available treatment. Glycomacropeptide (GMP) is a …
Pharmacological investigation of quinoxaline-bisthiazoles as multitarget-directed ligands for the treatment of Alzheimer's disease
SR Sagar, DP Singh, RD Das, NB Panchal… - Bioorganic …, 2019 - Elsevier
Alzheimer's disease (AD) is the most prevalent disease of old age leading to dementia.
Complex AD pathogenesis involves multiple factors viz. amyloid plaque formation …
Complex AD pathogenesis involves multiple factors viz. amyloid plaque formation …
Overcoming the exacerbating effects of ranitidine on NSAID-induced small intestinal toxicity with quercetin: providing a complete GI solution
DP Singh, SP Borse, M Nivsarkar - Chemico-Biological Interactions, 2017 - Elsevier
There is a need to find/discover novel leads to treat complex and/or multi-factorial-
pathogenic disease (s) like Nonsteroidal anti-inflammatory drugs (NSAID)-induced …
pathogenic disease (s) like Nonsteroidal anti-inflammatory drugs (NSAID)-induced …
Co-administration of quercetin with pantoprazole sodium prevents NSAID-induced severe gastroenteropathic damage efficiently: Evidence from a preclinical study in …
DP Singh, SP Borse, M Nivsarkar - Experimental and Toxicologic Pathology, 2017 - Elsevier
Management of Nonsteroidal anti-inflammatory drug (NSAID)-induced gastroenteropathy
has emerged as a major medical and socioeconomic problem mainly because the highly …
has emerged as a major medical and socioeconomic problem mainly because the highly …
Medicinal Chemistry approaches of controlling gastrointestinal side effects of non-steroidal anti-inflammatory drugs. Endogenous protective mechanisms and drug …
P Tziona, P Theodosis-Nobelos… - Medicinal …, 2017 - ingentaconnect.com
Background: Non-steroidal anti-inflammatory drugs are the oldest and most widely used
medicines. However, their untoward effects, especially gastrointestinal toxicity, remain the …
medicines. However, their untoward effects, especially gastrointestinal toxicity, remain the …
Potential synergistic effects of quercetin with other phytoconstituents of Costus pictus (insulin plant) extract in the control of hyperglycemia and prevention of NSAID …
SP Borse, DP Singh, D Upadhyay… - Food and Chemical …, 2018 - Elsevier
There is a need of multifactorial management to treat T2DM. Till date, no clinically simulated
animal model and therapy for NSAID-induced gastroenteropathic damage (NSAID-iGD) in …
animal model and therapy for NSAID-induced gastroenteropathic damage (NSAID-iGD) in …