Recent Contributions of Mass Spectrometry-Based “Omics” in the Studies of Breast Cancer

S Banerjee, M Hatimuria, K Sarkar, J Das… - Chemical Research …, 2023 - ACS Publications
Breast cancer (BC) is one of the most heterogeneous groups of cancer. As every biotype of
BC is unique and presents a particular “omic” signature, they are increasingly characterized …

Discovery of lipid profiles in plasma‐derived extracellular vesicles as biomarkers for breast cancer diagnosis

L Liu, M Kawashima, M Sugimoto, K Sonomura… - Cancer …, 2023 - Wiley Online Library
Lipids are a major component of extracellular vesicles; however, their significance in
tumorigenesis and progression has not been well elucidated. As we previously found that …

Alterations in lipid profile upon uterine fibroids and its recurrence

NM Tonoyan, VV Chagovets, NL Starodubtseva… - Scientific Reports, 2021 - nature.com
Uterine fibroids (UF) is the most common (about 70% cases) type of gynecological disease,
with the recurrence rate varying from 11 to 40%. Because UF has no distinct …

Enhancing precision medicine through clinical mass spectrometry platform

J Hristova, D Svinarov - Biotechnology & Biotechnological …, 2022 - Taylor & Francis
There is an extraordinary flood of new technologies in medicine nowadays. Sophisticated
diagnostics based on genome assays, mass spectrometry and cell sorting platforms are …

Comparison of the effectiveness of variable selection method for creating a diagnostic panel of biomarkers for mass spectrometric lipidome analysis

AO Tokareva, VV Chagovets… - Journal of Mass …, 2021 - Wiley Online Library
Hundreds of compounds are detected during untargeted lipidomics analysis. The potential
efficacy of lipids as disease markers makes it important to select the species with the most …

Analytical platforms for the determination of phospholipid turnover in breast cancer tissue: Role of phospholipase activity in breast cancer development

R Perestrelo, M Petkovic, CL Silva - Metabolites, 2021 - mdpi.com
Altered lipid metabolism has been associated with the progression of various cancers, and
aberrant expression of enzymes involved in the lipid metabolism has been detected in …

A Hierarchical Machine Learning Frame Work to Classify Breast Tissue for Identification of Cancer

JA Ruth, VGV Mahesh, R Uma, P Ramkumar - Proceedings of the 11th …, 2021 - Springer
In this work a study is conducted on the Breast tissues using machine learning algorithms to
identify the Breast cancer. The paper proposes a hierarchical two stage classification frame …

[HTML][HTML] Comparison of different machine learning methods and dimensionality reduction for classification astrocytoma and glioblastoma tissues by mass spectra

ES Zhvansky, AA Sorokin, DS Zavorotnyuk… - …, 2021 - f1000research.com
Background: Recently developed methods of ambient ionization allow rapid obtaining of
large mass spectrometric datasets, which have a great application in biological and medical …

Lipid Markers of Breast Tissue for the Diagnosis of Regional Metastatic Lesion

V Chagovets, A Tokareva, N Starodubtseva… - 2021 - researchsquare.com
The development of minimally invasive, non-traumatic and stable approaches for the
diagnosis of metastatic lesions of regional lymph nodes upon breast cancer is of great …