Cancer development and its response to therapy are regulated by inflammation, which
either promotes or suppresses tumor progression, potentially displaying opposing effects on …

Simple Summary The relationship between the immune system and tumours is currently one
of the most studied topics in the field of cancer. Previously, it was thought that a tumour could …

Immune system acts as a host defensive mechanism protecting against attacking pathogens
and transformed cells, including cancer cells. Th17 cells are a specific subset of T helper …

At the turn of the century, researchers discovered a unique subtype of T helper cells that
secretes IL-17 and defined it as Th17. The latest study found that Th17 cells play both …

Inflammation is a double-edged sword exhibiting multifaceted functions. On one hand, it
either induces tumor cell apoptosis, or establishes tumor dormancy by inhibiting tumor cell …

Background To investigate the differential expression of PD-1 and PD-L1 in salivary gland
tumors (SGTs, malignant and benign subtypes) and determine their association with the …

Abstract T helper 17 (Th17) cells were first described as a novel T helper cell lineage
independent from Th1 and Th2 subsets. Th17 cells play vital roles in inflammation and tumor …

Gastric cancer tissue-derived mesenchymal stem cells (GC-MSCs) are important resident
stromal cells in the tumor microenvironment (TME) and have been shown to play a key role …

Purpose The purpose of this study is to define if tumor-infiltrating lymphocytes (TILs) and
tumor-associated macrophages (TAMs) could represent potential predictors of lymph node …

The roles of inflammation and inflammatory cells such as Th17 cells in the development and
progression of cancer have been extensively studied. However, the results have been …