Piezoelectric single crystal ultrasonic transducers for biomedical applications

Q Zhou, KH Lam, H Zheng, W Qiu, KK Shung - Progress in materials …, 2014 - Elsevier
Piezoelectric single crystals, which have excellent piezoelectric properties, have extensively
been employed for various sensors and actuators applications. In this paper, the state-of-art …

[HTML][HTML] Recent Advancements in High-Frequency Ultrasound Applications from Imaging to Microbeam Stimulation

MG Kim, C Yoon, HG Lim - Sensors, 2024 - mdpi.com
Ultrasound is a versatile and well-established technique using sound waves with
frequencies higher than the upper limit of human hearing. Typically, therapeutic and …

[HTML][HTML] Sensitization of nerve cells to ultrasound stimulation through Piezo1-targeted microbubbles

X Shen, Z Song, E Xu, J Zhou, F Yan - Ultrasonics Sonochemistry, 2021 - Elsevier
Neuromodulation by ultrasound (US) has recently drawn considerable attention due to its
great advantages in noninvasiveness, high penetrability across the skull and highly …

Acoustic levitation and manipulation by a high-frequency focused ring ultrasonic transducer

X Chen, KH Lam, R Chen, Z Chen, X Qian… - Applied Physics …, 2019 - pubs.aip.org
Recently, acoustic levitation for non-contact micro-particle manipulation has been attracting
great interest in physical, biological, and medical applications. Among the state-of-the-art …

A novel therapeutic instrument using an ultrasound-light-emitting diode with an adjustable telephoto lens for suppression of tumor cell proliferation

H Choi, JM Ryu, S Choe - Measurement, 2019 - Elsevier
A new therapeutic instrument using ultrasound and a light-emitting diode with an adjustable
optical lens was introduced for suppressing HeLa cell proliferation. A focused-type …

[HTML][HTML] Modulation of anti-angiogenic activity using ultrasound-activated nutlin-loaded piezoelectric nanovectors

Ö Şen, A Marino, C Pucci, G Ciofani - Materials Today Bio, 2022 - Elsevier
Angiogenesis plays a fundamental role in tumor development, as it is crucial for tumor
progression, metastasis development, and invasion. In this view, anti-angiogenic therapy …

Direct and sustained intracellular delivery of exogenous molecules using acoustic-transfection with high frequency ultrasound

S Yoon, MG Kim, CT Chiu, JY Hwang, HH Kim… - Scientific reports, 2016 - nature.com
Controlling cell functions for research and therapeutic purposes may open new strategies for
the treatment of many diseases. An efficient and safe introduction of membrane …

Acoustic stimulation by shunt-diode pre-linearizer using very high frequency piezoelectric transducer for cancer therapeutics

H Choi, S Choe - Sensors, 2019 - mdpi.com
In this paper, we proposed cancer cell acoustic stimulation by shunt-diode pre-linearizer
scheme using a very high frequency (≥ 100 MHz) piezoelectric transducer. To verify the …

A feasibility study of in vivo applications of single beam acoustic tweezers

Y Li, C Lee, R Chen, Q Zhou, KK Shung - Applied physics letters, 2014 - pubs.aip.org
Tools that are capable of manipulating micro-sized objects have been widely used in such
fields as physics, chemistry, biology, and medicine. Several devices, including optical …

Focused ultrasound stimulates ER localized mechanosensitive PANNEXIN-1 to mediate intracellular calcium release in invasive cancer cells

NS Lee, CW Yoon, Q Wang, S Moon… - Frontiers in Cell and …, 2020 - frontiersin.org
Focused ultrasound (FUS) is a rapidly developing stimulus technology with the potential to
uncover novel mechanosensory dependent cellular processes. Since it is non-invasive, it …