Oral drug delivery platforms for biomedical applications
Oral administration is perhaps the most commonly used and acceptable route for drug
delivery to patients, mainly due to its non-invasiveness, simplicity, and versatility …
delivery to patients, mainly due to its non-invasiveness, simplicity, and versatility …
[HTML][HTML] Potassium-competitive acid blockers: advanced therapeutic option for acid-related diseases
N Inatomi, J Matsukawa, Y Sakurai, K Otake - Pharmacology & therapeutics, 2016 - Elsevier
Abstract Acid-related diseases (ARDs), such as peptic ulcers and gastroesophageal reflux
disease, represent a major health-care concern. Some major milestones in our …
disease, represent a major health-care concern. Some major milestones in our …
Acid‐inhibitory effects of vonoprazan 20 mg compared with esomeprazole 20 mg or rabeprazole 10 mg in healthy adult male subjects‐a randomised open‐label cross …
Y Sakurai, Y Mori, H Okamoto… - Alimentary …, 2015 - Wiley Online Library
Background Proton pump inhibitors (PPI s) are widely used for the treatment of acid‐related
diseases. Vonoprazan is a member of a new class of acid suppressants; potassium …
diseases. Vonoprazan is a member of a new class of acid suppressants; potassium …
Randomised clinical trial: safety, tolerability, pharmacokinetics and pharmacodynamics of repeated doses of TAK‐438 (vonoprazan), a novel potassium‐competitive …
H Jenkins, Y Sakurai, A Nishimura… - Alimentary …, 2015 - Wiley Online Library
Summary Background TAK‐438 (vonoprazan) is a potassium‐competitive acid blocker that
reversibly inhibits gastric H+, K+‐ATP ase. Aim To evaluate the safety, tolerability …
reversibly inhibits gastric H+, K+‐ATP ase. Aim To evaluate the safety, tolerability …
Safety, tolerability, pharmacokinetics, and pharmacodynamics of single rising TAK-438 (vonoprazan) doses in healthy male Japanese/non-Japanese subjects
Y Sakurai, A Nishimura, G Kennedy… - Clinical and …, 2015 - journals.lww.com
OBJECTIVES: To evaluate safety, tolerability, pharmacokinetics, and pharmacodynamics of
TAK-438 (vonoprazan, a potassium-competitive acid blocker) in healthy male subjects …
TAK-438 (vonoprazan, a potassium-competitive acid blocker) in healthy male subjects …
Salivary microbiome with gastroesophageal reflux disease and treatment
N Kawar, SG Park, JL Schwartz, N Callahan, A Obrez… - Scientific reports, 2021 - nature.com
The effect of oral microbial composition on periodontal health and on systemic health has
been, and is being established. The oral microbiome, in turn, can be altered by local and …
been, and is being established. The oral microbiome, in turn, can be altered by local and …
The efficacy and tolerability of a triple therapy containing a potassium-competitive acid blocker compared with a 7-day PPI-based low-dose clarithromycin triple …
S Suzuki, T Gotoda, C Kusano, K Iwatsuka… - Official journal of the …, 2016 - journals.lww.com
OBJECTIVES: This study evaluated the efficacy and tolerability of potassium-competitive
acid blocker (P-CAB), a new class of gastric acid inhibitory agents, as first-lineH …
acid blocker (P-CAB), a new class of gastric acid inhibitory agents, as first-lineH …
Antisecretory, Gastroprotective, Antioxidant and Anti-Helicobcter Pylori Activity of Zerumbone from Zingiber Zerumbet (L.) Smith
Background Zingiber zerumbet Smith is a perennial herb, broadly distributed in many
tropical areas. In Malaysia, it's locally known among the Malay people as “lempoyang” and …
tropical areas. In Malaysia, it's locally known among the Malay people as “lempoyang” and …
[HTML][HTML] Role of acid suppression in acid-related diseases: proton pump inhibitor and potassium-competitive acid blocker
H Mori, H Suzuki - Journal of neurogastroenterology and motility, 2019 - ncbi.nlm.nih.gov
Proton pump inhibitors are commonly utilized for the treatment of gastric acid-related
diseases, such as gastroesophageal reflux disease, peptic ulcer disease, and Helicobacter …
diseases, such as gastroesophageal reflux disease, peptic ulcer disease, and Helicobacter …
[HTML][HTML] Evidence for gastroprotective, anti-inflammatory and antioxidant potential of methanolic extract of Cordia dichotoma leaves on indomethacin and stress …
The Cordia dichotoma (CD) is having anticancer and other pharmacological effects as it
contains mainly flavonoids. The present study was aimed to demonstrate the …
contains mainly flavonoids. The present study was aimed to demonstrate the …