Irritable bowel syndrome (IBS) is a functional disorder which affects a large proportion of the
population globally. The precise etiology of IBS is still unknown, although consensus …

Traditionally, irritable bowel syndrome has been considered to be a disorder with no known
underlying structural or biochemical explanation, but this concept is likely to be outdated. In …

The intestinal barrier is complex and consists of multiple layers, and it provides a physical
and functional barrier to the transport of luminal contents to systemic circulation. While the …

Functional bowel disorders are highly prevalent disorders found worldwide. These disorders
have the potential to affect all members of society, regardless of age, sex, race, creed, color …

Irritable bowel syndrome (IBS) is a common disorder characterized by altered gut function
and often is accompanied by comorbid anxiety. Although changes in the gut microbiota have …

We provide a general framework for understanding functional gastrointestinal disorders
(FGIDs) from a biopsychosocial perspective. More specifically, we provide an overview of …

Objectives: This trial investigated whether probiotics improved mood, stress and anxiety in a
sample selected for low mood. We also tested whether the presence or severity of irritable …

Communication between the brain and gut is not one-way, but a bidirectional highway
whereby reciprocal signals between the two organ systems are exchanged to coordinate …

Background: Increased intestinal permeability due to barrier dysfunction is supposed to
cause microbial translocation which may induce low-grade inflammation in various …

Bidirectional signalling between the gastrointestinal tract and the brain is regulated at
neural, hormonal, and immunological levels. This construct is known as the brain–gut axis …