Exploring the past, present, and future of anti-angiogenic therapy in glioblastoma

AB Zhang, K Mozaffari, B Aguirre, V Li, R Kubba… - Cancers, 2023 - mdpi.com
Simple Summary Glioblastoma is the most common malignant primary brain tumor. Despite
technological advancements and modern therapeutic agents used for treatment, the …

A narrative review of placental contribution to adverse pregnancy outcomes in women with polycystic ovary syndrome

AS Kelley, YR Smith… - The Journal of Clinical …, 2019 - academic.oup.com
Context Polycystic ovary syndrome (PCOS) is the most common endocrinopathy of
reproductive-aged women. In pregnancy, women with PCOS experience increased risk of …

Single-cell RNA sequencing reveals regulatory mechanism for trophoblast cell-fate divergence in human peri-implantation conceptuses

B Lv, Q An, Q Zeng, X Zhang, P Lu, Y Wang, X Zhu… - PLoS …, 2019 - journals.plos.org
Multipotent trophoblasts undergo dynamic morphological movement and cellular
differentiation after conceptus implantation to generate placenta. However, the mechanism …

Immunological tolerance in the evolution of male pregnancy

J Parker, A Dubin, R Schneider, KS Wagner… - Molecular …, 2023 - Wiley Online Library
The unique male pregnancy in pipefishes and seahorses ranges from basic attachment
(pouch‐less species: Nerophinae) of maternal eggs to specialized internal gestation in …

Maternal cadmium exposure during late pregnancy causes fetal growth restriction via inhibiting placental progesterone synthesis

YW Xiong, HL Zhu, Y Nan, XL Cao, XT Shi, SJ Yi… - Ecotoxicology and …, 2020 - Elsevier
Cadmium (Cd) is a major environmental pollutant. Maternal Cd exposure throughout
pregnancy caused fetal growth restriction (FGR). However, the pivotal time window of Cd …

The impact of early pregnancy metabolic disorders on pregnancy outcome and the specific mechanism

XZ Zhu, ZM Deng, FF Dai, H Liu, YX Cheng - European Journal of Medical …, 2023 - Springer
Miscarriage is the most common complication of pregnancy. The most common causes of
early miscarriage are chromosomal abnormalities of the embryo, maternal endocrine …

N-acetylcysteine alleviates cadmium-induced placental endoplasmic reticulum stress and fetal growth restriction in mice

MY Guo, H Wang, YH Chen, MZ Xia, C Zhang, DX Xu - PLoS One, 2018 - journals.plos.org
Cadmium (Cd) is a developmental toxicant that induces fetal growth restriction (FGR).
Placental endoplasmic reticulum (ER) stress is associated with FGR. This study investigated …

Genome-wide DNA methylation analysis in primary antiphospholipid syndrome neutrophils

E Weeding, P Coit, S Yalavarthi, MJ Kaplan… - Clinical …, 2018 - Elsevier
Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by
thromboembolic events and pregnancy loss. We sought to characterize the DNA methylation …

Epithelial membrane protein 2 governs transepithelial migration of neutrophils into the airspace

WC Lin, KM Gowdy, JH Madenspacher… - The Journal of …, 2020 - Am Soc Clin Investig
Whether respiratory epithelial cells regulate the final transit of extravasated neutrophils into
the inflamed airspace or are a passive barrier is poorly understood. Alveolar epithelial type 1 …

Unraveling the structures, functions and mechanisms of epithelial membrane protein family in human cancers

N Zhang, HP Zhu, W Huang, X Wen, X Xie… - … hematology & oncology, 2022 - Springer
Abstract Peripheral myelin protein 22 (PMP22) and epithelial membrane proteins (EMP-1,-2,
and-3) belong to a small hydrophobic membrane protein subfamily, with four …