[HTML][HTML] Chronic HCV infection and inflammation: Clinical impact on hepatic and extra-hepatic manifestations

R Zampino, A Marrone, L Restivo… - World journal of …, 2013 - ncbi.nlm.nih.gov
The liver has a central role in regulating inflammation by its capacity to secrete a number of
proteins that control both local and systemic inflammatory responses. Chronic inflammation …

[HTML][HTML] Hepatitis C: From inflammatory pathogenesis to anti-inflammatory/hepatoprotective therapy

H Li, MH Huang, JD Jiang, ZG Peng - World journal of …, 2018 - ncbi.nlm.nih.gov
Hepatitis C virus (HCV) infection commonly causes progressive liver diseases that
deteriorate from chronic inflammation to fibrosis, cirrhosis and even to hepatocellular …

Hepatocellular carcinoma mechanisms associated with chronic HCV infection and the impact of direct-acting antiviral treatment

S Dash, Y Aydin, KE Widmer… - Journal of hepatocellular …, 2020 - Taylor & Francis
Hepatitis C virus (HCV) infection is the major risk factor for liver cirrhosis and hepatocellular
carcinoma (HCC). The mechanisms of HCC initiation, growth, and metastasis appear to be …

[HTML][HTML] Molecular mechanisms of hepatitis C virus–induced hepatocellular carcinoma

T Vescovo, G Refolo, G Vitagliano, GM Fimia… - Clinical Microbiology …, 2016 - Elsevier
Hepatitis C virus (HCV) is a major leading cause of hepatocellular carcinoma (HCC). HCV-
induced hepatocarcinogenesis is a multistep process resulting from a combination of …

Exploring the JAK/STAT signaling pathway in hepatocellular carcinoma: unraveling signaling complexity and therapeutic implications

H Park, S Lee, J Lee, H Moon, SW Ro - International Journal of Molecular …, 2023 - mdpi.com
Hepatocellular Carcinoma (HCC) continues to pose a substantial global health challenge
due to its high incidence and limited therapeutic options. In recent years, the Janus Kinase …

Risk of hepatocellular carcinoma after HCV clearance by direct-acting antivirals treatment predictive factors and role of epigenetics

L Rinaldi, R Nevola, G Franci, A Perrella, G Corvino… - Cancers, 2020 - mdpi.com
Direct-acting antivirals (DAAs) induce a rapid virologic response (SVR) in up to 99% of
chronic hepatitis C patients. The role of SVR by DAAs on the incidence or recurrence of …

Innate and adaptive immunopathogeneses in viral hepatitis; crucial determinants of hepatocellular carcinoma

MYW Zaki, AM Fathi, S Samir, N Eldafashi, KY William… - Cancers, 2022 - mdpi.com
Simple Summary Infections with Hepatitis B and Hepatitis C viruses are usually
asymptomatic and although some patients undergo resolution of infection, the majority do …

Role of inflammation in virus pathogenesis during pregnancy

A Chudnovets, J Liu, H Narasimhan, Y Liu… - Journal of …, 2020 - Am Soc Microbiol
Viral infections during pregnancy lead to a spectrum of maternal and fetal outcomes, ranging
from asymptomatic disease to more critical conditions presenting with severe maternal …

Identification of effective anti-HCV and anti-HIV royal jelly constituents and their acute toxicity evaluation in Albino rats

NH Habashy, AF Hamouda, MMA Serie - Food and Chemical Toxicology, 2023 - Elsevier
Few studies on royal jelly's (RJ) antiviral activities and toxicity have been conducted. Here,
we investigated the antioxidant properties of RJ that was fractionated into soluble fraction …

Cross-talk between TNF-α and IFN-γ signaling in induction of B7-H1 expression in hepatocellular carcinoma cells

N Li, J Wang, N Zhang, M Zhuang, Z Zong… - Cancer Immunology …, 2018 - Springer
Clinical benefit from immunotherapy of B7-H1/PD-1 checkpoint blockade indicates that it is
important to understand the regulatory mechanism of B7-H1 expression in cancer cells. As …