Natural and anthropogenic causes are continually growing sources of metals in the
ecosystem; hence, heavy metal (HM) accumulation has become a primary environmental …

Detection of toxic small molecule contaminants with sensitivity, accuracy, and specificity is a
challenging task. Traditionally used HPLC and mass spectrometry-based assays suffer from …

CRISPR-Cas systems have been widely used in genome editing and transcriptional
regulation. Recently, CRISPR-Cas effectors are adopted for biosensor construction due to its …

Patulin (PAT) is an unsaturated lactone mycotoxin primarily produced by Penicillium
expansum and Aspergillus clavatus. Given the potential health risks and economic losses …

An aptamer is a single-stranded DNA or RNA that binds to a specific target with high binding
affinity. Aptamers are developed through the process of systematic evolution of ligands by …

Malathion is an organophosphate chemical (OPC) and a toxic contaminant that adversely
impacts food quality, human health, biodiversity, and the environment. Due to its small size …

Considering the trans-cleavage capabilities, high-specificity and programmability, the
CRISPR-Cas system has been recognized as a valuable platform to develop the next …

Pollution by the pesticide fipronil (FPN) and three potentially stronger toxicological
metabolites (FPNs) threatens ecological balance and human health. Thus, broad-specificity …

Portable biosensors have emerged as powerful diagnostic tools for analyzing sensitive
biological samples. These biosensors offer sensitive detection capabilities by utilizing …

Small-molecule contaminants, such as antibiotics, pesticides, and plasticizers, have
emerged as one of the substances most detrimental to human health and the environment …