[HTML][HTML] MicroRNA-based diagnosis and therapy
MicroRNAs (miRNAs) are a group of endogenous non-coding RNAs that regulate gene
expression. Alteration in miRNA expression results in changes in the profile of genes …
expression. Alteration in miRNA expression results in changes in the profile of genes …
RNAi-based therapeutics and novel RNA bioengineering technologies
RNA interference (RNAi) provides researchers with a versatile means to modulate target
gene expression. The major forms of RNAi molecules, genome-derived microRNAs …
gene expression. The major forms of RNAi molecules, genome-derived microRNAs …
MicroRNA-mediated regulation of glucose and lipid metabolism
P Agbu, RW Carthew - Nature reviews Molecular cell biology, 2021 - nature.com
In animals, systemic control of metabolism is conducted by metabolic tissues and relies on
the regulated circulation of a plethora of molecules, such as hormones and lipoprotein …
the regulated circulation of a plethora of molecules, such as hormones and lipoprotein …
RNA drugs and RNA targets for small molecules: principles, progress, and challenges
RNA-based therapies, including RNA molecules as drugs and RNA-targeted small
molecules, offer unique opportunities to expand the range of therapeutic targets. Various …
molecules, offer unique opportunities to expand the range of therapeutic targets. Various …
The COSMIC Cancer Gene Census: describing genetic dysfunction across all human cancers
Z Sondka, S Bamford, CG Cole, SA Ward… - Nature Reviews …, 2018 - nature.com
Abstract The Catalogue of Somatic Mutations in Cancer (COSMIC) Cancer Gene Census
(CGC) is an expert-curated description of the genes driving human cancer that is used as a …
(CGC) is an expert-curated description of the genes driving human cancer that is used as a …
Regulation of microRNA function in animals
LFR Gebert, IJ MacRae - Nature reviews Molecular cell biology, 2019 - nature.com
Since their serendipitous discovery in nematodes, microRNAs (miRNAs) have emerged as
key regulators of biological processes in animals. These small RNAs form complex networks …
key regulators of biological processes in animals. These small RNAs form complex networks …
Regulation of microRNA biogenesis and its crosstalk with other cellular pathways
T Treiber, N Treiber, G Meister - Nature reviews Molecular cell biology, 2019 - nature.com
MicroRNAs (miRNAs) are short non-coding RNAs that inhibit the expression of target genes
by directly binding to their mRNAs. miRNAs are transcribed as precursor molecules, which …
by directly binding to their mRNAs. miRNAs are transcribed as precursor molecules, which …
[HTML][HTML] Overview of microRNA biogenesis, mechanisms of actions, and circulation
MicroRNAs (miRNAs) are a class of non-coding RNAs that play important roles in regulating
gene expression. The majority of miRNAs are transcribed from DNA sequences into primary …
gene expression. The majority of miRNAs are transcribed from DNA sequences into primary …
miRNAs insights into rheumatoid arthritis: Favorable and detrimental aspects of key performers
Rheumatoid arthritis (RA) is a severe autoimmune inflammation that mostly affects the joints.
It's a multifactorial disease. Its clinical picture depends on genetic and epigenetic factors …
It's a multifactorial disease. Its clinical picture depends on genetic and epigenetic factors …
[HTML][HTML] MicroRNA: A signature for cancer progression
MicroRNAs (miRNAs) are a group of small non-coding RNAs that post-transcriptionally
control expression of genes by targeting mRNAs. miRNA alterations partake in the …
control expression of genes by targeting mRNAs. miRNA alterations partake in the …