Whispering-gallery mode optoplasmonic microcavities: From advanced single-molecule sensors and microlasers to applications in synthetic biology
MC Houghton, SV Kashanian, TL Derrien… - ACS …, 2024 - ACS Publications
Optical microcavities, specifically, whispering-gallery mode (WGM) microcavities, with their
remarkable sensitivity to environmental changes, have been extensively employed as …
remarkable sensitivity to environmental changes, have been extensively employed as …
Protein amyloids develop an intrinsic fluorescence signature during aggregation
We report observations of an intrinsic fluorescence in the visible range, which develops
during the aggregation of a range of polypeptides, including the disease-related human …
during the aggregation of a range of polypeptides, including the disease-related human …
From single-molecule spectroscopy to super-resolution imaging of the neuron: a review
For more than 20 years, single-molecule spectroscopy has been providing invaluable
insights into nature at the molecular level. The field has received a powerful boost with the …
insights into nature at the molecular level. The field has received a powerful boost with the …
Detection of protein aggregate morphology through single antifouling nanopore
In this report, we investigate the potential offered by nanopores for the detection of proteins
aggregates. We focus our study on model proteins, such as ß-lactoglobulin, lysozyme and …
aggregates. We focus our study on model proteins, such as ß-lactoglobulin, lysozyme and …
Modulating amyloids' formation path with sound energy
A Kozell, D Eliaz, A Solomonov… - Proceedings of the …, 2023 - National Acad Sciences
Protein folding is crucial for biological activity. Proteins' failure to fold correctly underlies
various pathological processes, including amyloidosis, the aggregation of insoluble proteins …
various pathological processes, including amyloidosis, the aggregation of insoluble proteins …
Correcting chromatic offset in multicolor super-resolution localization microscopy
M Erdelyi, E Rees, D Metcalf, GSK Schierle, L Dudas… - Optics express, 2013 - opg.optica.org
Localization based super-resolution microscopy techniques require precise drift correction
methods because the achieved spatial resolution is close to both the mechanical and optical …
methods because the achieved spatial resolution is close to both the mechanical and optical …
Probing amyloid protein aggregation with optical superresolution methods: from the test tube to models of disease
CF Kaminski, GS Kaminski Schierle - Neurophotonics, 2016 - spiedigitallibrary.org
The misfolding and self-assembly of intrinsically disordered proteins into insoluble amyloid
structures are central to many neurodegenerative diseases such as Alzheimer's and …
structures are central to many neurodegenerative diseases such as Alzheimer's and …
Molecular basis of the inhibition and disaggregation of thermally-induced amyloid fibrils of human serum albumin by an anti-Parkinson's drug, benserazide …
TI Chandel, A Masroor, MK Siddiqi, IA Siddique… - Journal of Molecular …, 2019 - Elsevier
This study summarises the results of multifactorial analysis of the inhibition/destabilization of
human serum albumin (HSA) amyloid fibrils by an anti-Parkinson's drug, benserazide …
human serum albumin (HSA) amyloid fibrils by an anti-Parkinson's drug, benserazide …
Stability of lysozyme in aqueous extremolyte solutions during heat shock and accelerated thermal conditions
The purpose of this study was to investigate the stability of lysozyme in aqueous solutions in
the presence of various extremolytes (betaine, hydroxyectoine, trehalose, ectoine, and firoin) …
the presence of various extremolytes (betaine, hydroxyectoine, trehalose, ectoine, and firoin) …
In Silico Preliminary Association of Ammonia Metabolism Genes GLS, CPS1, and GLUL with Risk of Alzheimer's Disease, Major Depressive Disorder, and Type 2 …
JWD Griffin, Y Liu, PC Bradshaw, K Wang - Journal of Molecular …, 2018 - Springer
Ammonia is a toxic by-product of protein catabolism and is involved in changes in glutamate
metabolism. Therefore, ammonia metabolism genes may link a range of diseases involving …
metabolism. Therefore, ammonia metabolism genes may link a range of diseases involving …